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Indydiscoverynetwork.org

ANTICHOLINERGIC COGNITIVE BURDEN SCALE
Developed by the Aging Brain Program of the IU Center for Aging Research Drugs with Possible
Anticholinergic Effects
Drugs with Definite
Generic Name
Brand Name
Generic Name
Brand Name
Complete References:
Boustani MA, Campbell NL, Munger S, Maidment I, Fox GC. Impact of anticholinergics on the aging brain: a review and practical application. Aging Health. 2008;4(3):311-20. 2. Campbell N, Boustani M, Limbil T, Ott C, et al. The cognitive impact of anticholinergics: a clinical review. Clinical Interventions in Aging. 2009;4(1):225-33 Do not reproduce without permission – contact rmanns@regenstrief.org
The following represents a list of alternative medications developed by an The following represents a list of alternative medications developed by an interdisciplinary group of specialists within the Aging Brain Program at Indiana interdisciplinary group of specialists within the Aging Brain Program at Indiana University. These suggestions do not supersede clinical judgment, and are intended to University. These suggestions do not supersede clinical judgment, and are intended to assist clinicians in practicing in acute health care settings who provide care for patients assist clinicians in practicing in acute health care settings who provide care for patients with cognitive impairment such as dementia, mild cognitive impairment or delirium. with cognitive impairment such as dementia, mild cognitive impairment or delirium. Recommended alternatives to medications with Definite Anticholinergic Properties
Recommended alternatives to medications with Definite Anticholinergic Properties
Allergies or itching:
Hold during acute care stay – consider
Loratadine or Cetirizine orally
scheduling toileting
Insomnia:
Trazadone orally
Reflux disorders:
Esomeprazole orally
(Clinical judgment to consider if Painful abdominal cramps:
Morphine orally or IV
Depression:
Sertraline or Citalopram orally
Neuropathic pain:
Consider ondansetron IV or PO, or
Gabapentin orally
Metoclopramide PO
Insomnia:
Trazadone orally
Acetaminophen or oxycodone/
(Recommendation does not apply to acetaminophen
chronic use for psychiatric diagnosis) Acute care environment:
Morphine sulfate orally or IV
Haloperidol orally or IM for 72
hours only
Seizures:
Consult neurology for alternative
Neuropathic pain:
Gabapentin or levetiracetam orally
Movement disorders:
Mood disorders:
Dopamine agonists or levodopa
Consult psychiatry for alternative
For more information or permission to duplicate, please contact:
Noll Campbell, PharmD or Malaz A. Boustani, MD, MPH
Regenstrief Institute, Inc.
Do not reproduce without permission – contact
410 West 10th Street, Suite 2000
Indianapolis, IN 46202-3012
www.indydiscoverynetwork.com
Phone: (317) 423-5633 Fax: (317) 423-5695

Source: http://www.indydiscoverynetwork.org/resources/antichol_burden_scale.pdf

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