Ama medstyle stat! - fall 2007

AMA MEDSTYLE STAT!
By Dr. Abel Scribe PhD - Fall 2007
The American Medical Association (AMA) Manual of Style begins with this charming observation:
I never cease to be amazed by the general inability of physicians, other health professionals, andscientists to communicate through the written word. Their scholarly and creative ideas andinsightful data interpretation of them seem to get lost in the translation from brain to page.1(pv) No brainer? Those needing connective surgery from brain to page might wish to read “The Science of
Scientific Writing,” by G.D. Gopen and J.A. Swan, from the American Scientist, 1990. They argue “if the
reader is to grasp what the writer means, the writer must understand what the reader needs.” Available at
http://www.americanscientist.org/template/AssetDetail/assetid/23947?fulltext=true&print=yes
AMA STAT! CONTENTS
AMA-Style Page Format
General & AMA Conventions
Research Documentation
1. Title & Text Page
7. Abbreviations & Acronyms
Text Citations
2. Structured Abstract
8. Capitalization & Spacing
“Versioning”
3. Page Parameters
9. Compound Words
Reference Style Sheet
4. Headings (Cap Rule)
10. Emphasis: Italics/Quotes
Articles
5. Tables and Figures
11. Numbers & Measurements
Books & Chapters
6. Bullets & Lists
12. Quotations
Papers & References Works
13. Terminology
Web Sites & CDs
AMA Stat! is a quick reference to using the style of the American Medical Association in research
papers—papers drafted for conferences, classes, and seminars. It is based on the most recent 10th
edition of the AMA Manual of Style, 2007. The latest version and other style resources are available at
www.docstyles.com. Freeware Copyright 2007 by Dr. Abel Scribe PhD.
AMERICAN MEDICAL ASSOCIATION STYLE AT 10
The AMA Manual remains a heavy tome. The last edition weighed 3.0 pounds (to convert to kilograms
multiply by 0.45); the new one comes in at 4.2 pounds!1,2 This works out to 1032 pages, more even than
the Chicago Manual of Style.3 Alas, the rules and instructions for preparing research papers are scattered
throughout the volume. AMA Stat! seeks to capture the most essential features, neither an easy nor
certain task with a text so vast.
Significant changes to the style include the manner of presenting conventional clinical measurements
and the “versioning” of references to online sources. Conventional measures now require a conversion
factor to SI units (metric system) in the text. The AMA has thoughtfully provided the 18-page table of
conversion factors from the AMA Manual among the “Instructions for Authors” on their website (AMA
spells it Web site).4 Versioning adds multiple dates to Web references.
Changes readers might notice are the use of 2-letter postal abbreviations for states in references (AMAstyle had called for old style abbreviations, eg, Mich. for Michigan), and the use of lowercase letters inplace of symbols in tables (eg, asterisks, daggers, and the like). The old manual allowed numbers otherthan one to be written out, as in two-letter postal abbreviations, but no longer. This simply reflects long-standing practice observed in the pages of JAMA, a practice not widely shared by other major journals,such as the New England Journal of Medicine.
AMA style merges into minutiae with obscure rules. For example, the abbreviation for saint is
followed by a period when used in a person’s name, St. James, but not when used with the name of a
place, St Louis.1(p334) This suggests a style too obscure at the margins to usefully master, a product of
evolutionary diversity exploding through 10 generations, overseen by committee. AMA Stat! focuses on
main themes, with recourse to the New England Journal of Medicine, International Committee of Medical
Journal Editors (ICMJE) “Uniform Requirements,”5 and Chicago Manual of Style3 as circumstances merit.
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AMA STYLE PAGE FORMATS
1.0 Title and Text Page
The objective
is to present a paper in a format familiar to persons accustomed to reading the medical
literature even though no single style exemplifies a normative or generic format. As a result, research
papers should reasonably incorporate features that might be expected in a manuscript submitted for
review, and should be consistent in the use of whatever stylistic features adopted.
Figure 1. Title page and first text page for a paper with an unstructured abstract.
Final Manuscripts in AMA Style
Abel Scribe, PhD
Ganja College of Traditional Medicine
April 1, 2008
ABSTRACT
Reports of original data, reviews and, meta-analyses require a structured abstract of no more than 300 words. Other major manuscripts require as unstructured abstract of no more than 200 words that summarizes the objective, main points, and conclusions of the article. Abstracts are not required for editorials, commentaries, MAJOR SUBJECT HEADING
Final manuscripts differ from copy manuscripts in that they are presented in the format intended for the reader. Use block-paragraph spacing, with extra space before headings. Double-space the text; single-space block quotes and references.
Second-Level Heading
Copy manuscripts are read by typesetters and editors, who may have only a slight or passing interest in the subject. The first paragraph after a heading is not indented.
Third-level heading. If there is 1 heading or subheading at any level there
must be a second. Henry David Thoreau professed that “[n]o face which we can give to a matter will stead us so well . . . as the truth.”1(p217) However, Thoreau also anticipated evidence-based medicine, noting that [a]lert and healthy natures remember that the sun rose clear. It is never toolate to give up our prejudices. No way of thinking or doing, however ancient,can be trusted without proof. What everybody echoes, or in silence passes byas true to-day [sic], may turn out to be falsehood to-morrow [sic], meresmoke of opinion.1(p10) A second third-level heading. Write out ordinal numbers first through ninth,
as in second third-level heading. Number every page of the paper.
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2.0 Structured Abstract
An abstract
is required for most papers, though not all. Journals vary in their requirements; their
“Instructions for Authors” typically giving specific requirements. An unstructured abstract is presented in
Figure 1. In AMA style this is to be 200 words or less. Figure 2 shows a structured abstract drawn from
the ICMJE “Uniform Requirements for Manuscripts Submitted to Biomedical Journals.”5
Figure 2. Title page with a structured abstract in classic IMRAD form.
Title Page With a Structured AbstractAbel Scribe, PhDGanja College of Traditional MedicineApril 1, 2008 ABSTRACT
Introduction [Context]
The text of observational and experimental articles is usually (but not necessarily)divided into sections with the headings Introduction, Methods, Results, andDiscussion. This so-called “IMRAD” structure is not simply an arbitrary publicationformat, but rather a direct reflection of the process of scientific discovery. Longarticles may need subheadings within some sections (especially the Results andDiscussion sections) to clarify their content. Other types of articles, such as casereports, reviews, and editorials, are likely to need other formats.
Method [Design, Setting, and Participants]
An abstract (requirements for length and structured format vary by journal) shouldprovide the context or background for the study and should state the study’spurposes, basic procedures (selection of study subjects or laboratory animals,observational and analytical methods), main findings (giving specific effect sizes andtheir statistical significance, if possible), and principal conclusions. It shouldemphasize new and important aspects of the study or observations.
Present your results in logical sequence in the text, tables, and illustrations, giving themain or most important findings first. Do not repeat in the text all the data in thetables or illustrations; emphasize or summarize only important observations. Extra orsupplementary materials and technical detail can be placed in an appendix where itwill be accessible but will not interrupt the flow of the text; alternatively, it can bepublished only in the electronic version of the journal.
Discussion [Conclusions]
Emphasize the new and important aspects of the study and the conclusions thatfollow from them. Do not repeat in detail data or other material given in theIntroduction or the Results section. For experimental studies it is useful to begin thediscussion by summarizing briefly the main findings, then explore possiblemechanisms or explanations for these findings, compare and contrast the results withother relevant studies, state the limitations of the study, and explore the implicationsof the findings for future research and for clinical practice.
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IMRAD stands for Introduction, Method, Results, [and] Discussion. The ICMJE “Uniform Requirements”
note that “[t]his so-called ‘IMRAD’ structure is not simply an arbitrary publication format, but rather a direct
reflection of the process of scientific discovery.” The AMA uses slightly different terms, as shown in
brackets in Figure 2. When presenting a structured abstract begin the text on the next page, repeating the
title (and author information if you wish). The “Instructions for Authors” for AMA journals explain the
headings and organization required for various types of papers (eg, clinical trials, reviews, commentaries,
etc).4 The ICMJE “Uniform Requirements” note these sources of further information:5
Table 1. Reporting Guidelines for Specific Study Designs
http://www.consort-statement.org/stardstatement.htm Systematic reviews/meta-analyses http://www.consort-statement.org/Initiatives/MOOSE/moose.pdf http://www.consort-statement.org/Initiatives/MOOSE/moose.pdf 3.0 Page Parameters
Conference and class papers
differ from those submitted for review or publication in that (1) formal
disclosure statements and permissions tend to become brief notes added to the end of the text, before the
references; (2) the text is consolidated with abstracts, acknowledgments, tables, and figures embedded
rather than leading or trailing the text on separate pages; and (3) block paragraph spacing is used for
abstracts, tables, notes, quotes, and references.
Margins. One inch margins are required around the text. Leave the right margin unjustified.
Line Spacing. Block paragraph spacing is recommended for final manuscripts. Single space within the abstract, notes, titles and headings, block quotes, tables and figures, and references (everything butthe main text), double space before and after each single spaced block.
Fonts. JAMA specifies a 12-point or 10-point font. There is no requirement for the typeface. A serif typeface is commonly used in publication (eg, Times Roman). A sans serif typeface is then used withtables and figures.
Indents. Half-inch indents are standard.
Page Numbers. Every page of a research paper is numbered consecutively starting with the title page.
Do not change numbering systems through the text, even with lengthy data sets or appendixes.
Headers. A short title header goes at the top of the page, aligned with the page number or left margin.
This takes the place of the “running head” required of copy manuscripts.
4.0 Headings: Style and Capitalization
“Headings
reflect the progression of logic or the flow of thought in an article and thereby guide the reader.
Headings also help break up the copy, making the article more attractive and easier to read.”1(p26) Three
levels usually serve (Figs. 1 & 2). Additional levels can be added by following the second and third levels
with a heading in the same format in italics. Three styles of capitalization are used with headings
FIRST-LEVEL HEADINGS: ALL CAPS.
Every letter is capitalized. The text follows after a blank line; the paragraph is usually not indented.
Second-Level Headings: Heading-Headline Caps
“Capitalize [major words, and] 2-letter verbs, such as go, do, am, is, be. Note: The infinitive “to” is notcapitalized. Do not capitalize a coordinating conjunction, article, or preposition of 3 or fewer letters, exceptwhen it is the first word of the title.”1(p372) This rule applies to the main title, second-level headings, and thetitles of books. Blank lines go before and after the heading.
Third-level headings with sentence capitalization. This form capitalizes the first word, the first
word after a colon, and all proper nouns. Third-level headings (also known as run-in, run-on, paragraph,or sideheads) follow this form as do titles of articles in references. The heading is indented as aparagraph; need not be a complete sentence; must end with a punctuation mark. The text immediatelyfollows the heading (no blank line).
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5.0 Tables and Figures
Tables
presented in papers for publication now must be formatted using the table creation feature your
word processor. Published styles vary greatly from journal to journal, and yours may too, as long as you
are consistent in using the same format throughout the text. The style shown is classic AMA, with
features shared with other styles (eg, Chicago, APA). Complex tables require some forethought in their
construction; study the AMA Manual, chapter 4, “Visual Presentation of Data” for guidance.
Figure 3. Tables and figures in research papers.
Short Title Header 2
There is no one consistent format for presenting tables in AMA journals. The format suggested draws on features widely used in other styles, and is consistent with the official requirements of the AMA Manual. Table 2. Exercise and Body Weight by Educational Level: US 20025
Education level

Physical Exercise %
Body Weight %
Inactive
aActive is 20 minutes of vigorous physical activity 3 times a week; Some is less than active but morethan Inactive. Healthy body weight is a body mass index (BMI) less than 25; Heavy is 25 or more but6 less than 30; Overweight is 30 or more. Data from the Statistical Abstract of the United States: 2005.
Tables and figures are numbered independently and consecutively through the manuscript, appearing close after their first mention in the text. Use a contrasting sans-serif font such as arial or helvetica. Table notes are no longer referenced with symbols, but now require lowercase letters. Figures include graphs, diagrams, and images.
Figure 1. Cases of Hantavirus Pulmonary Syndrome7 Reported in the Four Corners
States (Arizona, Colorado, New Mexico, Utah): 1994-2001
Cases are reported by the calendar quarter of onset of symptoms.
All figures require a title and a caption or legend, an explanation of the scale or axes of a graph set below or to the side of the figure. Internal footnotes are not practical for most figures, although circles and arrows can be explained in the legend.
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Tables. “Each table should have a brief, specific, descriptive title, usually written as a phrase rather than
as a sentence, that distinguishes the table from other data displays in the article.”1(p84)
Table 3. Title in Bold Heading Caps: The Basic Parts of a Tablea
(Rule)

Stubhead
aNotes indicated by superscript letters.
“The field or body of the table presents the data. Each data entry point is considered a cell, which is theintersection of a column and a row. Table cells may contain numerals, text, symbols, or a combination ofthese . . . . Similar types of data should be grouped. Numbers that are added or averaged should beplaced in the same column. Text in field cells should be capitalized sentence style (ie, the first word iscapitalized and all that follow in the cell are lowercased).”1(p87) Table 4. Reported Cases: Hantavirus
Place tables in the text close after where they are first mentioned.
Pulmonary Syndrome 1993-2004a
Number tables consecutively. The table number is followed by a Spacing. Tables should be spaced for clarity. A contrasting font is also suggested, for example a sans-serif typeface (eg, arial, helvetica) in a table with a serif typeface (eg, Palitino or Times Abbreviations may be used in column headings or row studs.
Percentages in a column or row must add to 100 or a note of Units of measure should not change within columns unless the change is noted in the row stub and iscongruent with the column data; all numbers should be presented to the same number of decimal places.
See the section on numbers for rules on presenting significant digits and rounding in tables. • “In tables, units of measure, including the variability of the measurement if reported, should follow a comma in the table column heading or stub.”1(p95) In Table 4 the last row stub changes the units in theCases column to Age, mean (range), y. The y is the abbreviation for years.
Missing data and blank space in the table field (ie, and empty cell) may create ambiguity and should be avoided . . . . An ellipsis (. . .) may be used to indicate no data are available [or applicable].”1(p87) • Significance. “All P values should be reported as exact numbers to 2 digits past the decimal point, regardless of significance, unless they are lower than .01, in which case they should be presented to 3digits. Express any P values lower than .001 as P<.001. P values can never equal 0 or 1.”8 Footnotes are indicated by superscript lowercase letters; the old symbols are no longer used.
Figures include graphs, charts, photographs, illustrations, diagrams, and images.
Number all figures in the order of their citation in the text followed by Figure 2. Peromyscus maniculatus (deer
a title (a brief phrase, preferably no longer than 10 to 15 words).
• Include a legend (caption) for each photograph, graph, and illustration (maximum length, 40 words). For photomicrographs,include the type of specimen, original magnification or a scalebar, and stain. For gross pathology specimens, label any rulerswith units of measure.7 • The figure is cited in the text when first mentioned, for example, Figure 2 shows the deer mouse, carrier of the hantavirus SinNombre virus (SNV) in the United States.
A citation is required when the figure is adapted from another source.6 The image is about half scale.
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6.0 Bullets and Lists (Seriation)
Seriation is the itemization or enumeration of the parts to a series or an argument. The Chicago, APA,
and AMA styles refer to this as the process of enumeration. “Enumerate elements in a series to prevent
misreading or to clarify the sequence or relationship between elements, particularly when they are lengthy
or complex.”6(pp115–116)
Sentence seriation. A series or list of terms or phrases can be introduced following a colon in AMA style:either (a) marked by lowercased letters in italics with the parentheses in plain text; or (2) marked bynumbers, and (3) set in parentheses. Whatever style you adopt, be consistent throughout your text.
Paragraph seriation. If each element in the series requires a separate paragraph, these are set flush withthe left margin with each paragraph indented and numbered appropriately. An introductory clause orsentence ending with a colon typically introduces the series: 1 This form of seriation is useful in detailing and summarizing an argument, or perhaps the 2 Each element in the series may contribute to the general topic with extensive commentary.
3 This form of seriation is common in JAMA. It is used to present the parts of arguments, and also to summarize the conclusions of a study. It is rare in the NEJM.
“Bullets without enumeration may be used for emphasis and clarity when the specific order of the item is
not important. If the items are complete sentences, begin each item with a capital letter and end it with a
period.”1(p829) If the items do not form a sentence do not use a period; uppercase or lowercase the first
word to your preference; short lists are usually lowercased.
GENERAL AND AMA TEXT CONVENTIONS
7.0. Abbreviations
“The editors
of the AMA’s scientific publications discourage the use of abbreviations, acronyms, and
initialisms in their journals, with the exception of internationally approved and accepted units of measure
and some well-recognized clinical, technical, and general terms and symbols.”1(p442) Note, acronyms are
sounded as words, like NASA, while initialisms are sounded character by character, like CDC or FBI.
“Authors . . . should use good judgment, flexibility, and common sense when considering the use ofabbreviations. Abbreviations that some consider universally known may be obscure to others. Author-invented abbreviations should be avoided.”1(p442) • Expanded at first use. Acronyms/initialisms should be expanded at first use (written out in full) followed by the abbreviation in parentheses. Subsequently only the abbreviation is used. “Note: Theexpanded form . . . is given in lowercase letters, unless the expansion contains a proper noun, is aformal name, or begins a sentence (capitalize the first word only).”1(p444) • Familiar acronyms. Some groups are better known by their acronym than their full name, for example, WHO (World Health Organization) or CDC (Centers for Disease Control). But, “to avoid confusion,the names of all organizations should be expanded at the first mention in the text . . . with theabbreviation following immediately in parentheses.”1(p458) • Lower cased. “The expanded form of an abbreviation is given in lowercase letters, unless the expansion contains a proper noun, is a formal name, or begins a sentence (capitalize first word only).” • Beginning a sentence. “Avoid using abbreviations at the beginning of a sentence unless the expansion is cumbersome.”1(p501) That is, write “AIDS research has demonstrated . . .” in preferenceto “Acquired immune deficiency syndrome research has demonstrated . . .” • Headings, subheadings. “Do not use an abbreviation as the sole term in a subheading. Also avoid introducing an abbreviation in a subheading.”1(p501) Instead, write the term out and repeat it in thefollowing text to introduce the acronym.
Plurals. Write the plural form of an acronym without an apostrophe. For example, write “the Master of Business Administration (MBA) program is popular because MBAs command high starting salaries.” • Possessives. If the full term is possessive, the acronym in parentheses should also be possessive.
For example: “The American Medical Association’s (AMA’s) style manual has a mass of 1.9 kg.” • Places, States, and Addresses. “Names of US states, territories, and possessions should be spelled out in full when they stand alone.”1(p451) “At first mention in the text the names of the appropriate Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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country should follow the name of a city whenever clarification of location is thought to be important forthe reader.”1(p453) • States (Addresses & References). “Use 2-letter abbreviations for US state and Canadian province names in addresses (with US ZIP Codes and Canadian postal codes) and in references . . . . but notin the text [emphasis added].”1(p451) • Scholarly and Latin Abbreviations. Latin abbreviations such as etc, eg, and ie may be used only in parenthetical notes or references, otherwise spell out the equivalent term. For example, “Authoritiessupport this rule (eg, the Chicago Manual of Style).” Do not use periods in these abbreviations.
AMA “style for abbreviations rarely calls for the use of periods.”1(p442) Punctuation is not used
with any AMA abbreviations other than initials in names, or when quoted from another source! Medical journals. “Abbreviate and italicize names of journals. Use capital letters. Abbreviate
according to the listing in the PubMed Journals database.”1(p48) This is the List of Journals Indexed byMedline, formerly the Index Medicus, published by the National Library of Medicine. It is available (free) attheir website in PDF format. The volume is also listed on the AMA style page at www.docstyles.com witha link to the document. There is a separate volume for online journals.
8.0 Capitalization & Spacing
“Words are capitalized sparingly but conventionally in the scientific publications of the AMA.”2(p231) The
common rule is to capitalize terms when they refer proper nouns or to specific things: the East Coast, the
Congressional Budget Office, the Beck Depression Inventory. But when these terms are generalized, they
are lowercased: the coast, the budget office, a depression inventory.
Words following a colon. If a formal statement follows a colon, capitalize the first word. But, “in the caseof a question, capitalization of the first word can be left to the author’s personal style.”2(p241) In book titlesthe first word after a colon is capitalized. But, “for journal articles the subtitle begins with a lowercaseletter.”2(p34) For example, Krause RM. The origin of plagues: old and new. Science. 1992;257:1073-1078.
Special words. “Do not capitalize the following words, even when used as specific designations unless
they are used as part of a heading or title:”1(p379)
Heading caps. “Capitalize [in the text] major words in titles, subtitles, and headings of publications, parts
of publications, musical compositions, plays (stage and screen), radio and television programs, movies,
paintings and other works of art, software programs, Web sites, electronic systems, trademarks and
names of ships, airplanes, spacecraft, awards, corporations, and monuments.”1(p372) Titles of some
publications are formatted differently in references (see sec 16).
• “Do not capitalize a coordinating conjunction, article, or preposition of 3 letters or less, except when it is the first or last word in a title or subtitle.” • But, “in titles and headings, capitalize 2-letter verbs, for example, go, do, am, is, be.” Sentence caps capitalize just the first letter of the first word, the first word after a colon, and proper nouns
in a title, label, or phrase. For example, Breaking ground, breaking through: The strategic plan for mood
disorders research of the National Institute of Mental Health
. AMA style does not capitalize the first word
after a colon in article titles in references.
Compound Words? “In titles, subtitles, table heads, centerheads, sideheads, and line art, do not capitalizethe second part of a hyphenated compound in the following instances:”1(p373) • Do not capitalize “if either part is a hyphenated prefix of suffix.” For example, Anti-infective Drugs.
• Do not capitalize “if both parts together constitute a single word.” For example, X-ray films (check a dictionary to determine if the compound is recognized as a single word).
Capitalize both parts in all other circumstances. For example, “Client-Centered Therapy,” Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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Geographical Names. Capitalize geographic names when they refer to specific places.
• “Capitalize names of cities, towns, counties, states, countries, continents, islands, airports, peninsulas, bodies of water, mountains and mountain ranges, streets, parks, forests, canyons, dams,and regions.”1(p374) • Do not capitalize generic nouns used in the plural. For example, write “the Suez Canal” in the singular, but write “the Suez and Panama canals . . .” in the generalized plural.
• “Compass directions are not capitalized unless they are generally accepted terms for regions.”1(p375) For example, “although he lives in the West, and has adopted the mannerisms of a westerner rightdown to his cowboy boots, he grew up east of Rochester, New York.” Names with Prefixes. “Surnames that contain certain prefixes or particles (eg, von, de, La, van) are
spelled and capitalized according to the preference of the persons named.”1(p45)
Seasons and Holidays. “Do not capitalize the names of the seasons. . . . Capitalize the recognized
holidays and calendar events.”1(p377) For example, the last day of fall ends with the winter solstice closely
followed by Christmas.
Sociocultural Designations. “Capitalize the names of languages, nationalities, ethnicities, political
parties, religions, and religious denominations. Do not capitalize political doctrines (conservative,
progressive). Do not capitalize white or black as a designation of race.”1(p375) Do not hyphenate
compound terms, either as nouns or adjectives, for example, Anglo American, Hispanic American, Serbo
Croation, and so forth.
Tests. The word test is not usually capitalized except when it is part of the official name of the test.
Always verify exact names of any tests with the author or with reference sources.”1(p377) Specific forms are
capitalized, eg, the Beck Depression Inventory; generic terms are not capitalized when the generalized
form is used: the Beck inventory. Statistical tests are not capitalized except for proper nouns: a
goodness-of-fit test, the Fischer exact probability test.
9.0 Compound Words
Compound words
are two or more words that work together in a specified order. This order cannot be
reversed or rearranged without destroying the compound word’s meaning. Many compounds are
hyphenated when used as adjectives, but not as nouns. A dictionary is the best guide to spelling and
usage. If it is not in the dictionary it is not likely a hyphenated compound.
Full-time compound words are hyphenated whatever their role in a sentence--as an adjective or a noun.
These are called orthographic compounds. “The court-martial hearing is set for 1000 hours. The hearingwill determine whether a court-martial is warranted.” Court-martial is a full-time compound word (as is full-time). Consult a dictionary.
Conditional compounds are hyphenated as adjectives, but not when used as nouns.
1. Adjectival compound. “The counselor suggested a role-playing technique to reduce the stress of encounters, but cautioned that role playing alone would not solve the problem.” Role playing is acompound adjective, but not a compound noun. He was reading at the ninth-grade level in the sixthgrade.
2. Add a hyphen to any prefix attached to a proper noun, capitalized abbreviation, or number. For example, the post-Freudian era, the pre-1960s civil rights movement, the pro-HMO lobby.1(p347) 3. Fractions. “Common fractions are expressed with hyphenated words, whether the fraction is used as an adjective or a noun. Mixed fractions [ie, common fractions greater than 1, such as 3½] are typicalexpressed in numerals.”1(p824) 4. Made-up compound. A made-up-for-the-occasion compound is hyphenated as a modifier, but not when used in the predicate. The compound word was made up for the occasion. But when the termis “commonplace and familiar in everyday usage” [the hyphens are retained whatever the position ofthe term in the sentences].1(p345) For example, “the drug index was up-to-date.” 5. Numbers. “Hyphenate compound numbers from 21 to 99 and compound cardinal and ordinal numbers when written out, as at the beginning of a sentence.”1(p347) Twenty-seven nurses wererecognized for outstanding service.
6. Serial compounds. When two or more compound modifiers have a common base, this base is sometimes omitted in all but the last modifier, but the hyphens are retained. Long- and short-term Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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memory, 2-, 3-, and 10-min trials. When not used as modifiers the hyphen is dropped, for example,trials of 2, 3, and 10 minutes.1(p347) AMA Exception. A prefix may not stand alone before a contrasting unhyphenated prefix, eg, pre-
and postoperative care. Write preoperative and postoperative care.1(p347) Use sparingly. “When not otherwise specified, hyphens should be used only as an aid to the
reader’s understanding, primarily to avoid ambiguity.”1(p344) Prefixes. Through long usage most common prefixes do not require a hyphen: aftereffect, antifreeze,
cofounder, Internet, microwave, oversight, preempt, reexamine, supermarket, unbiased, underground
.
There are many exceptions. When in doubt check a dictionary. Note the following exceptions:
1. Ambiguous terms. Add a hyphen if the unhyphenated word or phrase would have a different meaning.
For example, does a “small bowel obstruction” refer to a small obstruction of the bowel, or anobstruction of the small bowel? If the latter it is a small-bowel obstruction. Words easily confusedinclude re-creation, re-treat, un-ionized.
2. Same two letters. If the prefix puts the same two letters together, a hyphen is sometimes inserted.
For example, write: anti-industrial, co-op, non-native, post-trial. But also write: cooperative,coordinate, nonnegotiable, overrate, overreach, overrule, reelect, unnamed.
3. Superlatives-diminutives. Some prefixes, best-, better-, ill-, lesser-, little-, well-, are hyphenated when they precede the noun they modify, but are not hyphenated when preceded by a modifier, or whenused as a predicate adjective. The ill-advised attack failed, the strategy was ill advised.
The following prefixes always require a hyphen: The following common prefixes are not joined by hyphens except when they precede a proper noun, acapitalized word, or an abbreviation:”1(p349) 10.0 Emphasis: Italics & Quotes
Add Emphasis with Italics.
Emphasize a keyword or phrase in your text by placing it in italics. The next
time an emphasized term or phrase is used it should be in plain text. Emphasis may be added to a word
or phrase in a quotation by placing it in italics. When this is done the note [italics added] must be inserted
in brackets next to or near the word or phrase emphasized.
Use this technique sparingly. It is generally not appropriate to place an entire sentence in italics nor to follow a sentence with an exclamation point. There are few, if any, instances in research writing wheresuch extensive emphasis is appropriate.
Quotation Marks. “Do not use quotation marks when emphasizing a word, when using a non-English
word, when mentioning a term [word] as a term, or when defining a term. In these instances, italics are
preferred.”1(p360)
No Quotes. “Quotation marks used around words to give special effect or to indicate irony are usually Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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But if you must. . . “Coined words, slang, nicknames, and words or phrases used ironically or facetiously may be enclosed in quotation marks at first mention. Thereafter omit quotationmarks.”1(p360) For example, “versioning” is the practice of noting several dates in references to onlinesources in AMA style.
Common words used in a special sense. “Enclose in quotation marks a common word used in a special technical sense when the context does not make the meaning clear.”1(p361) For example, a“ragged-right” margin is preferred in manuscripts.
Foreign words. Use quotation marks for the literal translation or definition of non-English words. The non-English term itself is placed in italics the first time it is used. For example, the name of the capitalof Ethiopia, Addis Ababa, literally translated means “new flower.” • Titles. “In the text, use quotation marks to enclose titles of short poems, essays, lectures, radio and television programs, songs, the name of an electronic file, parts of published works (chapters, articlesin a periodical), papers read at meetings, dissertations, theses, and parts of the same article (eg, the“Results” section).1(p361) 11. Numbers & Measurements
“Numerals
should be used to express numbers in most circumstances. Exceptions are numbers that
begin a sentence, title, subtitle, or heading; common fractions, accepted usage such as idiomatic
expressions, numbers used as pronouns, and other uses of the number “one” in running text; ordinals first
through ninth; and numbers spelled out in quotations or published titles.”1(p823)
Note. The AMA penchant for using numerals for all numbers under 10 is not followed by other major journals, such as the New England Journal of Medicine.
• “The word one should be spelled out when used as a pronoun or noun.”1(p824) • Ordinal numbers. “The numerical expression of commonly used ordinals (1st, 2nd, 3rd, 4th, etc) may appear jarring and interrupt the flow of text. For this reason ordinals first through ninth are spelledout.”1(p825) • Beginning a sentence. Write out numbers that begin a sentence, heading, title, or column heading in a table. If possible, rewrite the sentence or heading to avoid this problem.
Consecutive numbers. When two numbers must be presented together write one with words or rewrite the sentence. For example write: “There were twelve 16-year-olds in the clinical trial.” Do notwrite “There were 12 16-year-olds. . . .” • Measures & units must agree. When writing out numbers, accompanying units of measure must also be written out (and vice versa). For example, write: “Twenty degrees centigrade was the maximumtemperature at which the vaccine could be stored.” Or write: “The maximum temperature at which thevaccine could be stored was 20 °C.” Do not write twenty °C, or 20 degrees centigrade.
Decimal fractions. Numbers less than 1.0 must have a leading 0 before the decimal point, as with 0.6 kg (not .6 kg). An exception is made when a number cannot be greater than 1 or less than zero, as inthe probability P < .001.
Full dates when written in the text or in references are written in US format--month, day, year; “ August 21, 2001.” Other date formats follow the general rules for numbers. For example, write“applications were accepted from the 3rd to 23rd of August” or, “from the third to sixth of April.” • Rounded large numbers. Large rounded numbers usually combine numerals and words. “About 8 million people were affected by the drought.” • Compound numbers. Hyphenate compound written numbers from twenty-one to ninety-nine, and compounds with a number as the first element. For example, “We tested twenty-five 50 g samples.”(Note, a hyphen is never used in SI units,” 50 g samples,” even when the number is an adjective.) • “Common fractions are expressed with hyphenated words, whether the fraction is used as an adjective or a noun. Mixed fractions [ie, common fractions greater than 1, such as 3½] are typicallyexpressed in numerals.”1(p824) • Plurals. Form the plurals of numbers by adding s or es, without an apostrophe, to words or figures. “ The gambler rolled several sixes in a row.” “The 1960s taught a generation about war first hand.” Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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Clinical Measurements (New!). “Most physicians and other health care professionals [in the US] use
conventional units for many common clinical measurements (eg, blood pressure), and many clinical
laboratories report most laboratory values by means of conventional units. Accordingly, some biomedical
publications, including JAMA and the Archives Journals, have adapted an approach for reporting units of
measure that includes a combination of SI units and conventional units.”1(p794)
“Laboratory values are expressed using conventional units of measure, with relevant SystèmeInternational (SI) conversion factors expressed secondarily (in parentheses) only at first mention. . . . Intables and figures, a conversion factor to SI should be presented in the footnote or legend.”1(p795) Forexample, the AMA Manual weight 4.2 pounds (to convert to kilograms multiply by 0.45). An exhaustivetable of conversion factors is available in the “Instructions for Authors” at the JAMA website and atwww.docstyles.com.
Significant Digits. Implicit in any number is that it is accurate to the degree of precision shown. “When
numbers are expressed in scientific and biomedical articles, they should reflect the degree of accuracy of
the original measurement. Numbers obtained from mathematical calculations should be rounded to
reflect the original degree of precision.”1(p851) For example, “for a scale accurate to 0.1 kg a weight [sic]
should be expressed as 75.2 kg not 75.23 kg.”
AMA Rounding Rule. AMA style likes even numbers. “If the digit to the right of the last significant digit is
less than 5, the last digit is not changed. If the last digit is greater than 5, the last significant digit is
rounded up. . . . If the digit immediately to the right of the last significant digit is 5, with either no digits or
all zeros after the 5, the last significant digit is rounded up if it is odd and not changed if it is even. . .
47.7500 becomes 47.8; 47.65 becomes 47.6.”1(p851)
Inclusive Numbers. When expressing an inclusive range of numbers in your text do not use a dash or
hyphen, write to or through instead, unless the use of the hyphen is absolutely clear. Write: “The IQ range
of the first group was 86 to 112.” In measurements, a hyphen can be mistaken for a minus sign.
“Digits should not be omitted when indicating a span of years or page numbers in the text.”1(p827) For example, some journals drop digits from the second number in a range: 1134-39. AMA writes 1134-1139.
Le Système International d’Unitiés (SI) is the governing international standard for measurement in the
sciences. The National Institute of Standards and Technology (NIST) publishes their Guide for the Use of
the International System of Units (SI),
available online at: http://physics.nist.gov/Document/sp811.pdf.
The current link is also available at www.docstyles.com.
SI numbers have three parts: the numerical value, the prefix or multiplier, and the unitsymbol or abbreviation (e.g., 25.3 kg). Numbers are always formatted in plain text (noitalics), there is always a space after the value (never a hyphen), there is never aperiod after the units (except at the end of a sentence).
Numerical values are presented without commas in SI notation. For example, the distance betweenChicago and Denver is 1600 km (not 1,600 km). The km stands for kilo-meters. The prefix kilo indicatesthe units are multiplied by 1000. There are about 1.6 kilometers to a mile. If it is important for clarity youcan note the conventional US measure in parentheses after the SI number: 1600 km (1,000 miles).
• There is always a space after the numerical value, and only a space (eg, the temperature was 25 °C, • SI numbers are not subject grammatical conventions other than those of the SI. Only a space may follow a numerical value, no hyphens, no exceptions! Do not hyphenate a measure used as anadjective, as for example, “a 5-mg dose” is incorrect (see Taylor, 1995, sec. 7.2b).
• Units of measure are always abbreviated when presented with numerical values, but written out when noted in the text without a numerical value. For example, a liter is about a quart; "It took 22 L to top
off the gas tank."
• Numerical values less than one are preceded by a zero. For example, one yard is 0.91 m, or about three inches short of a meter. An exception is made for statistical values that by definition cannot begreater than one, for example a probability statistic such as p < .05.
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12. Quotations
Quotations
must be placed within quotation marks or indented as a block quote. All quotations must
include a citation referring the reader to the source document. Quotations should be integrated into the
flow of your text, and may be edited to do so. Quotations must be exact replicas of the original subject to
the editing options noted below. Citations in the original should be reproduced in the quote but are not
included in the list of references.
Run-On Quotes. Shorter quotes, less than four lines of text, continue with the text inside quotation
marks. These are referred to as run-on quotations in AMA style.
Commas, colons. Put closing quotation marks outside commas and periods, but inside colons and • Terminal punctuation. Put question marks, dashes, and exclamation points inside quotation marks Block Quotes. “If material quoted from text or speeches is longer that 4 line of text, the material should
be set off in a block, ie, in reduced type and without quotation marks. Paragraph indents are generally not
used unless the quoted material is known to begin a paragraph. Space [blank lines] is often added both
above and below these longer quotations.”1(p365)
Quotation marks. Quotations marks are not used around block quotes, but the block is usually set off from the text by additional spacing above and below the block.
Block Indent. Block quotes are typically set 1/2 inch from the left margin in manuscripts, or the same distance as a paragraph indent. An additional paragraph indent is used on the first line only if it isfound in the original.
Spacing. Block quotes may be single spaced in research papers (double spaced before and after the quote). This block paragraph spacing may also be applied to references.
Edit Quotations. While obvious typical errors in a quotation are usually corrected without making a
special notation, strict adherence to the AMA manual requires even these aberrations to be noted. An
unusual word choice, concept, term, or spelling is quoted faithfully followed by the Latin term sic (thus), in
italics and in brackets, immediately following. This example was actually found in the last (9th) edition of
the AMA manual: “Each reference should be cited in the text, tables, or figures in consecutive numerical
order by means of superscript arabic numberals [sic].”2(p30)
Brackets are required to indicate material or emphasis added to a quote. For example, write “They [the Irish Republican Army] initiated a cease fire” or “[The Irish Republican Army] initiated a ceasefire.” • A change in capitalization to merge a quotation into the flow of your text must be indicated with brackets.1(p365) “[M]erge a quotation into the flow of your text.” • “The first word after the end punctuation mark and the ellipsis [within a quotation] should use original • Italics may be used to add emphasis to words or phrases within a quotation, or to the entire quotation.
When this is done a note is added to the quote in brackets at the end of the sentence [italics added].
Delete Text from a Quotation. Ellipsis points are used to indicate text omitted from a quotation. But
unless clarity demands it, do not use ellipsis points to begin or end a quotation.
Within a sentence. Three ellipsis points (periods with a single space before, between, and after each period) indicate material has been omitted within a sentence. For example, “The creature . . . walkslike a duck, and swims like a duck.” • Between sentences. A period and three ellipsis points are used to indicate material omitted between two sentences, or at the end of a sentence when the quote continues to a following sentence. “If acreature flies like a duck, quacks like a duck, walks like a duck. . . . It is, therefore, likely to be aduck.” • Beginning a sentence? In run-on quotes, the leading portions of a sentence opening a quotation, or the trailing portions of a sentence ending a quotation, may be excluded from a quotation withoutindicating an omission. “When a quoted phrase is an incomplete sentence, readers understand thatsomething precedes and follows; therefore ellipses are not used.”1(p365) Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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Beginning a sentence? In block quotes, “If the initial word(s) of the first sentence or [a] paragraph being quoted is omitted, begin that paragraph with a paragraph indentation and ellipses to indicatethat this is not the beginning of that paragraph.”1(p365) 13. Terminology
“Authors should avoid words and phrases that are unnecessarily elaborate, trendy, tautologic, or
euphemistic.”1(p381) Conciseness is a virtue in medical writing. Many journals restrict the length of
manuscripts; papers are evaluated for their brevity and clarity.
Age. The AMA Manual provides these definitions: Neonates or newborns are persons from birth to 1
month of age; infants are children from 1 month to 1 year; children are persons from 1 year to 12 years;
adolescents from 13 to 17 years; and adults are persons over 18.1(p410)
Designation of Persons. Language in its careless use can dehumanize people. “The careful writer
avoids generalizations and stereotypes and is specific when choosing words to describe people.”2(p265)
Aged/Elderly. “Because the term elderly connotes a stereotype, avoid using it as a noun.”1(p416) Refer to older persons, elderly patients, the elderly population not the old or the elderly.
Case/Patient/Subject. “A case is evaluated, documented, [managed], and reported. A patient is examined, undergoes testing, [is cared for], and is treated. A research subject is recruited, selected,sometimes subjected to experimental conditions, and observed.”1(p389) • Disabilities. “Avoid labeling (and thus equating) people with their disabilities or diseases (eg, the blind, schizophrenics, epileptics). Instead, put the person first.”1(p416) Instead of referring to diabetics, referto persons with diabetes; the disabled as persons with disabilities; the crippled, lame, or deformed arethe physically disabled or persons with physical disabilities.
Drugs. “Use nonproprietary names of drugs, devices, and other products, unless the specific trade name
of a drug is essential to the discussion.1(pp567-569) “[O]nly 1 drug name, the nonproprietary name, is regulated
internationally to ensure consistent usage and no duplication with other drugs. Once a drug has been
assigned a nonproprietary name, the nonproprietary name should always be used to refer to the drug.”1(p565)
Microorganisms. A distinction is made between taxonomic classification and nomenclature. This is
especially relevant in medicine where many microorganisms use taxonomic nomenclature that does not
reflect the phylogenetic relationships or evolutionary descent of a taxonomic system.
“Stylistic hallmarks of biological nomenclature differentiate scientific names form vernacular names.
These hallmarks are latinization, italics, and a 2-word term for species; the binomial, also called binary orbinominal, eg, Homo sapiens.
According to the international codes, initial capitals are used for all taxa, except for the second portion ofthe binomial. (That portion is called the specific name in the zoological code and the specific epithet in thebotanical and bacteriological codes.) Italics are always used for the genus and species components of thebinomial. Diacritical marks (accents) and ligatures (eg, æ) are not used.
“All codes capitalize scientific names of taxa but differ in italicizing higher taxa. The bacterial coderecommends italicizing all scientific names but recognizes that journals may wish to style all organismnames similarly. In JAMA and the Archives Journals, taxa above genus are not italicized. The followingexamples . . . illustrate the style in JAMA and the Archives Journals.”1(p742) Table 5. Taxonomic Classification Systems
The binomial is usually all that is noted in a text; the higher levels of the taxonomic classification aregenerally inferred unless describing a new species, new classification, or the phylogenetic relationshipbetween two or more species.
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• “After first mention of the binomial species name, abbreviate the genus portion of the name. (JAMA and the Archives Journals do not use a period.) Do not abbreviate the specific name. Do not begin asentence with an abbreviated genus name [or any abbreviation unless unavoidable]; either expand orreword.”1(p743) • When the genus is shared with a second organism do not abbreviate the genus until it is mentioned in full with both species. For example, “Staphylococcus aureus and Staphylococcus epidermidis may becomponents . . . in clinically significant infections, although S aureus is the more serious pathogen ofthe two.”1(p743) Do not abbreviate the specific name [eg, aureus and epidermidis in the example above], and do notabbreviate the genus name when used alone.”1(743) For example, “Staphylococcus bacteria are a commonsource of hospital-acquired infections.” Viruses. “Although the viral nomenclature code recommends italicizing all scientific virus names (ie,
species through order) codes for other organisms differ on using italics for names of higher taxa. For
reasons of internal consistency, JAMA and the Archives Journals do not italicize names of viral taxa above
genus. . . . [though the journals] do italicize formal viral genus and species names”1(p757) Vernacular
names are never italicized.
“Binomial Proposal. Formal virus species names do not currently [2007] follow the binomial style of otherorganisms, . . . which include the genus and specific epithet. Confusion exists between terms for abstractvirus species and actual virus entities, which are often distinguished only typographically. Virologists haveindicated a preference for a binomial style.”1(p759) World Wide Web & Internet Terminology. There are differences of opinion on what to capitalize and
what to hyphenate. The British Medical Journal truncates or closes just about everything. American
conventions tend to be conservative (linked to the publication cycle of style guides!).
e-mail. The hyphenated form is found in the AMA, APA, and CMS manuals. The e is never
uppercased except at the beginning of a sentence.
home page [homepage]. This is spelled open in the Chicago Manual.
Internet [Net]. Internet is a proper noun.
Web . . . . This is a proper noun. When Web is used in an open compound term (or with a hyphen
when used as an adjective), as in Web page design, Web is uppercased. When the compound termis closed, Web is usually spelled lowercased, as in webmaster.
Web page, Web site. These terms are still spelled open in AMA style.
webmaster, web. . . Most other Web terms (except Web ring) are spelled lowercased and closed
(without a hyphen)--webcam, webcast, webhead, webmail, webzine, webmaster, etc.
RESEARCH DOCUMENTATION
14. Text Citations
“Each reference should be cited in the text, tables, or figures in consecutive numerical order [as presented
in the text] by means of superscript arabic numerals.”1(p42) “Authors should always consult the primary
source and should never cite a reference that they themselves have not read.”1(p40)
1. Placement. In the text, a superscript citation number should appear after a comma or period, but before a colon or semicolon. While citations may be placed within a sentence, it is preferable to placethem at the end of a sentence unless accuracy and clarity demands otherwise.
2. Multiple citations. Multiple references can be cited by listing each in order in the superscript citation, separated by a comma. An inclusive range of references can be cited by separating the range with ahyphen. For example, “Profuse bleeding is generally indicative of an injury.”1,2-5,8,12 3. Page numbers. Specific page numbers within a source can be cited by placing the page reference in parentheses after the citation number. Several sources may be cited in a single superscript.1(p44), 2(p9) 4. Table & figures. References in table and figures are cited in sequence with those in the text. The numbering shifts to the table or figure after it is first mentioned in the text. All references in the tableor figure are cited in sequence. The numbering of citations then returns to the text and continues forsubsequent citations.
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5. Numbers & measures. “Avoid placing a superscript reference citation immediately after a number [numeral] or an abbreviated unit of measure to avoid any confusion between the superscript referencecitation and an exponent.”1(p43) 6. Authors noted. When mentioned in the text, only surnames of authors are used. For a 2-author reference list both surnames; for references with more than 2 authors or authors and a group, includethe first author’s surname followed by “et al,” “and associates,” “and coworkers,” or “and colleagues.”For example: Smith7 observed, Smith and Jones8 reported, Jones et al10 determined.
7. Titles noted. When titles are presented in the text they are place in heading caps (sec. 8), titles of books and similar publications are placed in italics; titles of articles are placed in quotation marks.
Parenthetical Citations. Unretrievable sources and news articles are cited in the text in parentheses.
These sources are not included in the reference list. For example: “Newspapers reported HMOs were
routinely denying basic care (eg, New York News, September 31, 2003:12; Washington Star, February 29,
2003:G1), and the Chicago Times (December 1, 2003;§2:2)” “Robert Smith, MD, found the paperwork
requirements of his HMO exasperating (personal communication, April 2007).”
15. “Versioning” Online Sources
AMA style now makes provision for referencing online sources that may change over the course of their
posting on the Internet. The AMA Manual calls this "versioning" [the quotes are in the original, p. 64]. The
Manual offers this block format for references:1(p64)
Author(s). Title. Journal Name [using National Library of Medicine abbreviations--see
14.10, Abbreviations, Names of Journals]. Year;volume(issue No.):inclusive pages.
URL [provide the URL in this field; no need to use "URL:" preceding it].
Published [date]. Updated [date]. Accessed [date].
The last line is particularly interesting. It is what the AMA Manual calls "versioning" [the quotes are in theoriginal, p. 64]. They are three distinct elements or dates, used as available and appropriate. Since theaccess date is always known it is always a part of the reference. The other two dates are included whenrelevant and/or available, as in this example: International Committee of Medical Journal Editors. Uniform requirements for manuscripts
submitted to biomedical journals: sample references. Bethesda, MD: United States
National Library of Medicine Web site. http://www.nlm.nih.gov/bsd/uniform_requirements.html.
Published July 9, 2003. Updated April 25, 2007. Accessed September 5, 2007.
The problem with this reference is that we have no idea what has changed. Without documentation of thechange (as is required in print journals) you have no way of assessing the importance of the revision. Ifthe original reported the correct dose was “10 g” and latter corrected it to “10 mg” the consequences maybe grave. But if the correction was for a minor spelling error the effect would be insignificant.
A paper that relies on ephemeral sources becomes a fleeting conjecture grounded in undocumented and changing content. This is too vague to be credible in scientific publication.
16. Reference List
“Reference to information that is retrievable is appropriately made in the reference list. This includes but is
not limited to (1) articles published or accepted for publication in scholarly or mass circulation print or
electronic journals, magazines, or newspapers, (2) books that have been published or accepted for
publication, (3) papers presented at professional meetings, (4) abstracts, (5) theses, (6) CD-ROMs, films,
videotapes and audiofiles, (7) package inserts or a manufacturer’s documentation, (8) monographs, (9)
official reports, (10) databases and Web sites, (11) legal cases, (12) patents, and news releases.”1(p41), 9(p29)
Authors & Editors. List up to six authors or editors. If there are more, list the first three, plus et al.
Invert all names–authors, editors, translators, compilers–first & middle initials trailing without periods. Ifthe author(s) represent a group, add the group name after the authors (follow the rule for using et al.).
Article Titles. Titles of articles, chapters, Web pages, and entries in reference works are set in sentence caps; in plain text without quotation marks or italics. Note, “for journal articles the subtitlebegins with a lowercase letter.”1(p47) • Book Titles. Titles of books, volumes, reference works, reports & bulletins, theses & dissertations are formatted in heading caps and set in italics.
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Journal Names. The names of journals are set in italics and abbreviated according to the List of Journals Indexed for Medline (formerly Index Medicus) published by the National Library ofMedicine.1(p19) A link is available at www.docstyles.com.
City: State. Include the 2-letter abbreviation for the state with all US cities and Canadian provinces, eg, New York, NY; Toronto, ON. Add the country with all other cites, eg, Paris, France; London,England. Do not list the state if it is part of the publisher’s name.1(p55) • Page Numbers. Do not omit digits from inclusive page numbers.1(p48),2(p35) • Uniform Resource Locators (URLs). “Use the URL that will that will take the reader most directly to the article, not a long search string and not a short, more general URL (one to the publisher’s homepage, for example)’ if a URL is provided, as close as possible to publication verify that the link stillworks”1(p64) Articles in Periodicals
One to Six Authors (Commentary, Online)
Krause RM. The origin of plagues: old and new. Science. 1992;257:1073-1078.
Barry JM. The site of origin of the 1918 influenza pandemic and its public health implications[Commentary]. J Translational Med. January 20, 2004;2(3):1-4. http://www.translational-medicine.com/content/2/1/3. Accessed November 18, 2005.
Mokdad AH, Bowman BA, Ford ES, Vinicor F, Marks JS, Koplan JP. The continuing epidemics ofobesity and diabetes in the US. JAMA. 2001;286:1195-1200.
According to the AMA Manual, “When citing an electronic document that also exists in print form, you should cite the version you consulted.2(p44) There are no examples of references to pdffacsimiles of print articles in the AMA Manual or in recent issues of JAMA. Cite as print? McGlynn EA, M.Asch S, Adams J, et al. The quality of health care delivered to adults in the UnitedStates. N Engl J Med. June 26, 2003;348(26):2635-2645.
Moher D, Schulz KF, Altman D; for the CONSORT Group. The CONSORT statement: revisedrecommendations for improving the quality of reports of parallel-group randomized trials. JAMA.
2001;285:1987-1991.
Centers for Disease Control and Prevention. Plan and operation of the Third National Health andNutrition Examination Survey, 1988-94. Vital Health Stat. 1994;1:1-307.
Hypericum Depression Trial Study Group. Effect of Hypericum perforatum (St. John’s Wort) in majordepressive disorder: a randomized controlled trial. JAMA. 2002;287:1807-1814.
Pope HG Jr, Ionescu-Pioggia M, Pope KW. Drug use and life style among college undergraduates: a30-year longitudinal study. Am J Psychiatry. 2001;158:1519-1521.
Chambers HF III, Winston LG. Mupirocin prophylaxis misses by a nose [editorial]. Ann Intern Med.
2004;140(6):484-486.
Annual smoking attributable mortality, years of potential life lost and economic costs: United States1995-1999. MMWR Morb Mortal Wkly Rep. 2002;51:300-303.
Alexander, GC, Werner, RM, Ubel, PA. The costs of denying scarcity [commentary]. Arch Intern Med.
2004;164:593-596.
Coyle JT. Use it or lose it--do effortful mental activities protect against dementia? [Perspective]. N EnglJ Med. 2003;348:2489-2490.
Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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Lofwall MR, Strain EC, Brooner RK, Kindbom KA, Bigelow GE. Characteristics of older methadonemaintenance (MM) patients [abstract]. Drug Alcohol Depend. 2002;66(suppl 1):S105.
Tor M, Turker H. International approaches to the prescription of long-term oxygen therapy [letter]. EurRespir J. 2002;20(1):242.
Visscher TL, Seidell JC. The public health impact of obesity. Annu Rev Public Health. 2001;22:355-375.
Yager J, reviewer. Am J Psychiatry. 2004;161:1137. Review of: Crawshaw R. Compassion's Way: ADoctor's Quest into the Soul of Medicine. Curfman GD, Morrissey S, Drazen JM. Notice of duplicate publication of [Park S-J, Shin WH, Ho DS,et al. A paclitaxel-eluting stent for the prevention of coronary restenosis. N Engl J Med. 2003;348:1537-1545]. N Engl J Med. 2003;348:2254.
Hyman DJ, Pavlik VN. Characteristics of patients with uncontrolled hypertension in the United States[erratum, N Engl J Med. 2002;346:544]. N Engl J Med. 2001;345:479-486.
Mansharamani M, Chilton BS. The reproductive importance of P-type ATPases [published correctionappears in Mol Cell Endocrinol. 2002;188(1-2): 22-5]. Mol Cell Endocrinol. 2001;183(1-2):123-126.
Gottlieb M. A free-for-all in swapping Medicaid for managed care. New York Times. October 2,1995:A1, A4.
Markoff J. Voluntary rules proposed to help insure privacy for Internet users. New York Times. June 5,1996. http://www.nytimes.com/library/cyber/week/yo5dat.html. Accessed April 1, 1998.
Relman AS, Angell M. America’s other drug problem. The New Republic. December 16, 2002:27-41.
Undisclosed settlement reached out of court in Michigan Biodyne civil suit. Psychiatric Times. March 1,1992:16.
Banit DM, Kaufer H, Hartford JM. Intraoperative frozen section analysis in revision total jointarthroplasty. Clin Orthop. 2002;(401):230-238.
McGlynn EA, Brook RH. Keeping quality on the policy agenda. Health Aff (Millwood). 2001;20(3):82-90.
Most journals are paged continuously through a volume. When they are not the number of the Bodenheimer T. The Oregon Health Plan--lessons for the nation: first of two parts. N Engl J Med.
1997;337:651-655.
Bodenheimer T. The Oregon Health Plan--lessons for the nation. N Engl J Med. 1997;337(pt 2):720-723.
Flanagin A, Winker MA, eds. Global health. JAMA. 2004;291(21, theme issue):2511-2664.
Ward P, Small I, Smith J, Suter P, Dutkowski R. Oseltamivir (Tamiflu) and its potential for use in theevent of an influenza pandemic. J Antimicrob Chemother. 2005;55(suppl 1):i5S-i21S.
Books & Chapters
Goldstein H. Multilevel Statistical Models. 2nd ed. New York, NY: Wiley; 1995.
Congressional Budget Office. Changes in the Living Arrangements of the Elderly: 1960-2030.
Washington, DC: US Government Printing Office; 1988.
Iverson C, Flanagin A, Fontanarosa PB, et al. American Medical Association Manual of Style: A Guidefor Authors and Editors. 9th ed. Baltimore, MD: Lippincott Williams & Wilkins; 1997.
Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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Kuhn, Thomas S. The Structure of Scientific Revolutions. 2nd ed. Chicago, IL: University of ChicagoPress; 1970.
Edited Book (Editors as Authors/Online) Beers MH, Berkow R, eds. The Merck Manual of Diagnosis and Therapy. 17th ed. 1999.
http://www.merck.com/pubs/mmanual/. Accessed January 17, 2003.
Breedlove GK, Schorfheide AM. Adolescent Pregnancy. 2nd ed. Wieczorek RR, ed. White Plains, NY:March of Dimes Education Services; 2001.
Wassenaar JD, Thran SL, eds. Physician Socioeconomic Statistics. 2000-2002 ed. Chicago, IL:American Medical Association; 2001.
Chapters in Edited Books (Volume & Edition) Davey Smith G, Egger M. Going beyond the grand mean: subgroup analysis in meta-analysis ofrandomised trials. In: Altman DG, ed. Systematic Reviews in Heath Care: Meta-analysis in Context .
2nd ed. London, England: BMJ Publishing; 2001:143-156.
Mills S. Herbal medicine. In: Lewith G, Jonas WB, Walach H, eds. Clinical Research inComplementary Therapies. Edinburgh, Scotland: Churchill Livingstone; 2002:211-227.
Reynolds RC, Stone J. On doctoring: the making of an anthology of literature and medicine. In: IssaacsSL, Knickman JR, eds. To Improve Health and Health Care. San Francisco, CA: Jossey-BassPublishers; 2002:chap 8. The Robert Wood Johnson Foundation Anthology; vol 5.
http://www.rwjf.org/publications/publicationPdfs/anthology2002/chap8.html. Accessed June 26, 2003.
Stephan WG. Intergroup relations. In: Lindzey G, Aronson E, eds. The Handbook of SocialPsychology. Vol. 2. 3rd ed. New York, NY: Random House; 1985:599-658.
Monographs, Proceedings, & References
Conferences (Papers Published & Unpublished) Braveman P, Cubbin C, Marchi KS, Egerter S. An approach to policy-oriented monitoring of equity inhealth. Paper presented at: The 130th Annual Meeting of the American Public Health Association;November 9-13, 2002; Philadelphia, PA.
Harnden P, Joffe JK, Jones WG, eds. Germ Cell Tumours V. Proceedings of the 5th Germ CellTumour Conference; September 13-15, 2001; Leeds, UK. New York, NY: Springer; 2002.
Gieseker KE, Miller LA, Bryan R, et al. Occupational exposure to hantavirus: knowledge, risk, behavior:a four-state review [abstract 33]. In: Program and Abstracts of the 4th International Conference onHFRS and Hantaviruses. Atlanta, GA: Centers for Disease Control; 1998:72.
Borkowski MM. Infant Sleep and Feeding: A Telephone Survey of Hispanic Americans [dissertation].
Mount Pleasant, MI: Central Michigan University; 2002.
Tamiflu (oseltamivir phosphate) Capsules and for Oral Suspension [package insert]. Basel,Switzerland: F Hoffmann-La Roche Ltd; 1999.
Bureau of the Census. Higher education price indexes: 1965–1991. In: Statistical Abstract of theUnited States: 1993. 113th ed. Table 277. Washington, DC: US GPO; 1993.
Filamin. In: Dorland’s Illustrated Medical Dictionary. 29th ed. Philadelphia, PA: W. B. Saunders;2000:675.
Johnson K. Hantaviruses. In: Evans AS, ed. Viral Infections of Humans: Epidemiology and Control. 3rded. New York, NY: Plenum Press, 1989:341-350.
Merriam-Webster Collegiate Dictionary. 10th ed. Springfield, MA: Merriam-Webster; 1993.
Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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Taylor BN. Guide for the Use of the International System of Units (SI). 1995 ed. Gaithersburg, MD:National Institute of Standards and Technology; April 1995. NIST Special Publication 811.
http://physics.nist.gov/Document/ sp811.pdf. Accessed June 25, 2003.
Web Pages & Electronic Resources
Anderson SC, Poulsen KB. Anderson’s Electronic Atlas of Hematology [CD-ROM]. Philadelphia, PA:Lippincott Williams & Wilkins; 2002.
Organisation for Economic Co-operation and Development. OECD Health Data 2004 [CD-ROM]. Paris,France: Organization for Economic Cooperation and Development; 2004.
Meta-analysis. In: MeSH Browser [database online]. Bethesda, MD: National Library of Medicine; 2002.
http://www.nlm.nih.gov/mesh/MBrowser.html. Accessed June 10, 2003.
Who’s Certified [database online]. Evanston, IL: The American Board of Medical Specialists, 2000.
http://www.abms.org/newsearch.asp. Accessed March 8, 2001.
Homeland Security Council. National Strategy for Pandemic Influenza. Washington, DC: TheWhitehouse; November 1, 2005. http://www.whitehouse.gov/homeland/pandemic-influenza.html.
Accessed November 2, 2005.
Foley KM, Gelband H, eds. Improving palliative care for cancer [monograph online]. Washington, DC:National Academy Press; 2001. http://www.nap.edu/books/0309074029/html/. Accessed July 9, 2002.
Morse SS. Factors in the emergence of infectious diseases. Emerg Infect Dis [serial online]. January-March 1995;1(1):7-15. http://www.cdc.gov/ncidod/EID/eid.htm. Accessed April 15, 2003.
Adobe Systems. Adobe Acrobat 5.0 User Guide for Windows and Macintosh. San Jose, CA: AdobeSystems Inc; 2000. http://www.adobe.com/products/readstep/. Accessed April 1, 2002.
Epi Info [computer program]. Version 3.3.2. Atlanta, GA: Centers for Disease Control and Prevention;February 9, 2005. http://www.cdc.gov/epiinfo.html. Accessed November 20, 2005.
Association of Cancer Online Resources, Inc. Cancer-Pain [homepage]. New York, NY: TheAssociation, 2001. http://www.cancer-pain.org/. Accessed July 9, 2002.
National Center for Complementary and Alternative Medicine. St. John’s Wort and the treatment ofdepression [Web page]. National Institutes of Health Web site. http://nccam.nih.gov/health/stjohnswort/. Accessed January 19, 2003.
World Health Organization. Confirmed human cases of avian influenza A(H5N1) since 28 January2004 [on the Internet]. January 26, 2005. http://www.who.int/csr/disease/avian_influenza/country/cases_table_2005_01_26/en/JE. Accessed November 16, 2005.
Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com
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REFERENCES CITED IN AMA STAT!
1. Iverson C, Christiansen S, Flanagan A, et al. American Medical Association Manual of Style. 10th ed.
New York, NY: Oxford University Press, 2007.
2. Iverson C, Flanagin A, Fontanarosa PB, et al, for the American Medical Association. American Medical
Association Manual of Style: A Guide for Authors and Editors
. 9th ed. Baltimore, MD: Lippincott Williams &
Wilkins; 1997.
3. The Chicago Manual of Style. 15th ed. Chicago, IL: University of Chicago Press; 2003.
4. JAMA instructions for authors. JAMA Web site. August 7, 2007. http://jama.ama-assn.org/misc/
ifora.dtl. Accessed September 7, 2007.
5. International Committee of Medical Journal Editors. Uniform requirement for manuscripts submitted to
biomedical journals: writing and editing for biomedical publication. Updated February 2006.
http://www.icmje.org/. Accessed September 15, 2007.
6. American Psychological Association. Publication Manual of the American Psychological Association.
5th ed. Washington, DC: American Psychological Association; 2001.
STATE & PROVINCIAL POSTAL CODES
AL Alabama
MO Missouri
AK Alaska
MT Montana
AS American Samoa
AZ Arizona
AR Arkansas
NH New Hampshire
CA California
CO Colorado
NM New Mexico
CT Connecticut
DE Delaware
NC North Carolina
DC District of Columbia
MD Maryland
ND North Dakota
FL Florida
MA Massachusetts
WA Washington
GA Georgia
OK Oklahoma
WV West Virginia
MN Minnesota
OR Oregon
MS Mississippi
WY Wyoming
AB Alberta
NB New Brunswick
BC British Columbia
ON Ontario
MB Manitoba
QB Québec (PQ)
Dr. Abel Scribe PhD - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - www.docstyles.com

Source: http://writingcenter.missouristate.edu/assets/WritingCenter/amastat.pdf

I - identificaÇÃo do medicamento:

BU_01 - 341547 ESTREVA® Gel estradiol hemiidratado APRESENTAÇÃO Gel - Embalagem contendo 1 frasco de 50 g com bomba dosadora. USO PERCUTÂNEO USO ADULTO COMPOSIÇÃO Cada 100 g do gel contém: estradiol* . . 0,1 g Excipiente q.s.p. . 100 g (*na forma de estradiol hemi-hidratado). Cada pressão na bomba dosadora libera 0,5 g do gel, o que

Consultancy report

Consultancy Report Ref: 6386 R01 Mr M Barter and Mr P WebberJoint Occupational Safety and Health UnitSteele CloseEastleighIn accordance with our qualityassurance procedures, this report iscountersigned by: Noise measurements of appliances and equipment Hampshire Fire and Rescue August 2000 ISVR Consultancy Services Institute of Sound and Vibration Research Contents Append

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