James a

JAMES A. SIMON, MD, CCD, NCMP, FACOG

PUBLICATIONS 2007-2010

Original Papers in Refereed Journals:

1. Gorrindo T, Lu Y, Pincus S, Riley A, Simon JA, Singer BH, Weinstein M. Lifelong menstrual histories are typically erratic and trending: a taxonomy. Menopause. 2007 Jan-Feb; 14(1):74-88. 2. Ferrell RJ, O’Connor KA, Holman DJ, Brindle E, Miller RC, Rodriguez G, Simon JA, Mansfield PK, Wood JW, Weinstein M. Monitoring reproductive aging in a 5-year prospective study: aggregate and individual changes in luteinizing hormone and follicle-stimulating hormone with age. Menopause. 2007 Jan-Feb;14(1):29-37. 3. Simon JA, Bouchard C, Waldbaum A, Utian W, Zborowski J, Snabes MC. Low dose of transdermal estradiol gel for treatment of symptomatic postmenopausal women: a randomized controlled trial. Obstet Gynecol. 2007 Mar;109(3):588-96. 4. Lewiecki EM, Simon JA. Clinical use of bone density testing. The Female Patient. 2007 5. Simon J and Snabes MC. Menopausal hormone therapy for vasomotor symptoms: balancing the risks and benefits with ultra-low doses of estrogen. Expert Opin. Investig. Drugs (2007) 16(12): 2005-2020. 6. Abdallah RT, Simon JA. Testosterone therapy in women: its role in the management of hypoactive sexual desire disorder. Int J Impot Res. 2007 Sep-Oct;19(5):458–63. Review. 7. Simon JA. Hormone therapy in the 21st century: clinical considerations for moving beyond oral therapy. Bringing Clarity to Current Trial Data. Women's Health Care. 2007;6(2):11-17. 8. Traish A, Guay A, Spark F, Simon JA, the Testosterone Therapy in Women Study Group. Are the Endocrine Society's clinical practice guidelines on androgen therapy in women misguided? A commentary. J Sex Med. 2007 Sep;4(5);1223-35. 9. Siris ES, Simon JA, Barton IP, McClung MR, Grauer A. Effects of risedronate on fracture risk in postmenopausal women with osteopenia. Osteoporosis Int. 2007 Oct 30; 19(5): 681-686. 10. Traish A, Guay AT, Spark RF, and the Testosterone Therapy in Women Study Group. Are the Endocrine Society’s Clinical Practice Guidelines on Androgen Therapy in Women misguided? A commentary. J Sex Med. 2007 Nov;4(6); 1782-3. 11. Hubayter Z and Simon JA. Testosterone therapy for sexual dysfunction in postmenopausal women. Climacteric 2008 May;11(3);181-191. Review. 12. Simon JA, Bachmann G, Goldstein S, Kaunitz AM. Osteoporosis management for the 13. Simon JA, Reape KZ, Wininger S, Hait H. Randomized, multicenter, double-blind, placebo-controlled trial to evaluate the efficacy and safety of synthetic conjugated estrogens B for the treatment of vulvovaginal atrophy in healthy postmenopausal women. Fertil Steril. 2008 Oct;90(4):1132-8. Epub 2007 Dec 3. 14. Simon JA, Nachtigall L, Gut R, E Lang, Archer DF, Utian W. Effective treatment of vaginal atrophy with an ultra-low dose estradiol vaginal tablet. Obstet Gynecol. Nov 2008. 112 (5): 1-8. 15. Simon J. All bisphosphonates are not the same: Potential reasons for clinical differences. Submitted to the Journal of Women’s Health and Gender Based Medicine. 2008. 16. Kingsberg SA, Simon, JA, Goldstein, I. The Current Outlook for Testosterone in the Management of Hypoactive Sexual Desire Disorder in Postmenopausal Women. J Sex Med 2008;5(suppl 4):182-193. 17. Simon JA and Reape KZ. Understanding the menopausal experiences of professional 18. Simon JA. Vulvovaginal atrophy: new and upcoming approaches. Menopause. 2009 19. Simon JA. Postmenopausal estrogen therapy: which route to take? Nat Clin Pract 20. Krapf JM and Simon JA. The role of testosterone in the management of hypoactive sexual desire disorder in postmenopausal women. Maturitas. 2009 Jul 20;63(3):213-9. Epub 2009 May 31. 21. Simon JA. Hypoactive Sexual Desire Disorder in Women: Implications for Family Practice. The Journal of Family Practice. 2009 (supplement) Jul; 58(7): 26-30. 22. Liu JH, Aguirre OA, Katz M, Kingsberg S, LaValleur J, Simon JA, Buch A, Lucas JD, Rodenburg CA. Treatment of naturally menopausal women with hypoactive sexual desire disorder: effect of transdermal testosterone. Menopause 2008 (in press) 23. Simon JA, Miller S. Low-dose (0.45 mg) synthetic conjugated estrogens, A is effective for managing vasomotor symptoms in postmenopausal women. Climacteric (in press). 24. Liu JH, Aguirre OA, Katz M, Kingsberg S, LaValleur J, Simon JA, Buch A, Lucas JD, Rodenburg CA. Treatment of naturally menopausal women with hypoactive sexual desire disorder: effect of transdermal testosterone. American Journal of Obstetrics and Gynecology. 2009 (submitted). 25. Simon JA, Nahum GG, Stanislaw H, Ignatovych T. Breast Cancer “Plunge” After Initial Publication of the WHI Results: An Alternative Explanation. Menopause (submitted).
BOOKS, CHAPTERS, PROCEEDINGS AND INVITED ARTICLES:

1. Simon JA, Snabes MC. Post-Menopausal Hormone Therapy-Improving the Risk-Benefit Ratio with Ultra-low Doses of Estrogen. US Endocrine Disease 2007:Issue 1;77-9. 2. Simon JA. Secondary Amenorrhea: Uses of Progesterone for Induction of Bleeding. Supplement to OBG Management. 2007 Feb:6-8. 3. Simon JA. Estradiol topical emulsion for the treatment of moderate-to-severe vasomotor symptoms associated with menopause. Women’s Health. 2007;3(1): 29-37. 4. Simon JA. Women, Hormones, and Therapy: A Practitioner's Guide to Balancing Benefits and Safety. A supplement. Highlights from a Symposium for ACOG Annual Meeting. San Diego, California. May 8, 2007. 5. Simon JA. Women, Hormones, and Therapy: A Practitioner's Guide to Balancing Benefits and Safety. A supplement. A DVD from a Symposium for ACOG Annual Meeting. San Diego, California. May 8, 2007. 6. Pinkerton JV, London AM, Schwartz DB, Simon JA. Considerations in prescribing oral estrogen therapy."Women's' Health Update," a supplement to Menopause Management. May-June 2007 7. Simon J. Hormone therapy in the 21st century: clinical considerations for moving beyond oral therapy. Women's Health Care. Annual Meeting of the Nurse Practitioners in Women’s Health (NPWH). A published supplement. Las Vegas, Nevada. 2007. 8. Simon, JA. Proceedings from the National Consumers League’s Women’s Health Forum: Navigating Health Information. The National Press Club. January 18, 2007, Washington, DC. 9. Simon J. A fresh look at hormone therapy: Toward a clearer understanding of menopause and hormone therapy. 75th Annual Conference of the American College of Osteopathic Obstetricians & Gynecologists (ACOOG), Grand Cypress, FL, March 28, 2008. 10. Simon JA. Selecting patients for transdermal therapy. Highlights of Supported Plenary Symposia Presented at the 18th Annual Meeting of The North American menopause Society. October 3-6, 2007, Dallas, TX; 13-6. Menopause Management. 2007; Mar/Apr.17(1): 13-16.
11. Simon, JA. Exogenous Progestogens Through the Life Cycle: With A Focus on Their
Role in Secondary Amenorrhea and Menopause. Introduction: Overview of Progesterone/Progestins. Women’s Health Care: A Practical Journal for Nurse Practitioners. 2007 Summer;6(4):7-12. 12. Simon, JA. Exogenous Progestogens Through the Life Cycle: With A Focus on Their Role in Secondary Amenorrhea and Menopause. Secondary Amenorrhea: Use of Progesterone to Induce Bleeding. Women’s Health Care: A Practical Journal for Nurse Practitioners. 2007 Summer;6(4):13-16. 13. Simon JA, Ravnikar V, Hess H, Murphy D. Hysterectomy and Surgical Menopause: A Management Plan Based on Expert Opinion. Contemp Ob Gyn. 2007 Sept. 14. Simon, JA. What Does the ESTHER Study Add to the Evidence? Transdermal Estrogen Therapy: Evidence and Update. A Supplement to The Female Patient. 2007 Nov:1-8. 15. Simon, JA, Ravnikar V. Transdermal Estrogen Therapy: Evidence and Update. A Supplement to The Female Patient. 2007 Nov:1-8. 16. Simon JA. Hormone therapy today: perception, attitudes, and evidence. Ob Gyn News: Clinical perspectives in intrauterine contraception and postmenopausal hormone therapy - highlights of a symposium. 2008. 4-8. 17. Simon J, Darney P, and Jensen J. Clinical Perspectives in Intrauterine Contraception and Postmentopausal Hormone Therapy – Highlights of a Symposia. Supplement to Ob Gyn News. 2008. 4-8. 18. Simon, J. Androgen Therapy After Menopause: Sex, Bone, Brawn, Breast, and Brain. A Rountable Discussion. 20th Annual Meeting of the North American Menopause Society (NAMS). San Diego, CA. October 2, 2009.
OTHER PUBLICATIONS

1. Simon JA. Introduction: An Overview of Progesterone and Progestins. Supplement to OBG Management: Uses of Progesterone Throughout a Woman’s Lifetime. 2007 Feb:3-5. 2. Simon, JA. Management issues. Menopause e-Consult. Progesterone, medroxyprogesterone and breast cancer risk: Is the any evidence of possible differences in breast cancer risk with estrogen and progetogin when the “P” is micronized progesterone “MP” rather than medroxyprogesterone acetate “MPA”? 2007 July;Vol. 3, Issue 3. 3. Simon JA. “If only WHI had kept to its premise -- but now it’s time for their mea culpa.” Letter to the Editor: Menopause Management. 2007 Nov-Dec; Vol. 16, No. 6:9. 4. Simon JA. Effectively treating atrophic vaginitis without compromising efficacy. 5. Simon JA, Reape KZ, Wininger S, Hait H. Randomized, multicenter, double-blind, placebo-controlled trial to evaluate the efficacy and safety of synthetic conjugated estrogens B for the treatment of vulvovaginal atrophy in healthy postmenopausal women. Fertil Steril. 2007 Nov 28. E-publication ahead of print. 6. Traish A. The author's response to guideline panel's comments. J Sex Med 2007;4:1784- 7. Simon JA. The Evolution of estrogen therapy: a modern-day management option for menopause. On-line program: www.pvupdate.com/hrt11/4/002 and DVD. 8. Simon JA, Montgomery-Rice V. Effectively treat atrophic vaginitis without compromising efficacy. Vaginitis Management Series Program sponsored by Novo Nordisk, Inc. On-line program at www.pvupdate.com/hrt11/m/002; DVD www.pvupdate.com/ht11/r/2002. 9. Independent Study Program: Together again: estrogens, progestogens, and menopause. 10. Simon, JA. Erratum: Letter to the Editor. Menopause e-Consult. 2008 Jan;Vol. 4, Issue 1. 11. Simon J. Unique Combination HT for the Symptomatic Postmenopausal Patient. ANGELIQ patients have seen effective, rapid relief from moderate to sever vasomotor symptoms (VMS) with a tolerable side effect profile. Webcast for ANGELIQ Medsite Interactive Learning Program. 12. Hodis HN, Simon JA. Changing Tides: New Insights into the Impact of HT. Charting a Course through Changing Tides. An Evidence-Based Examination of Hormone Therapy in Women’s Health. 2008 Fall. Monthly Prescribing Reference. 13. Simon JA. Pharmacologic Prevention and Treatment of Osteoporosis. The Female Patient 14. Simon JA. Letter to the Editor: “Crisis in Osteoporosis Care”. The Female Patient. 2009. 15. Simon J and Samander E. “Bioidentical Hormone Therapy: What Is It, Might It Have Advantages, and What We Simply Don't Know! Expert Interview with Dr. James A. Simon”. MedscapeCME Ob/Gyn & Women's Health. 2009 16. Simon JA. “Bone Mass and the Risk of Fracture: Menopause, Osteoporosis, and Bone Fracture”. Osteo Today: Reducing the Risk of Hip Fracture in Postmenopausal Gynecology Patients. 2009 17. Simon JA. “FSD: Does Surgically Induced Menopause Matter?”. 18. Simon JA. Editorial: Vulvovaginal atrophy: new and upcoming approaches. Menopause. 19. Hess H, London A, Moore A, and Simon J. Pharmacologic Treatment Options for Menopausal Symptoms. The Female Patient 2009 (Supplement): 1-8. 20. Simon JA. PV Updates Publishing (2009, September 14). Raise Awareness and Understanding of Female Sexual Dysfunction. Female Sexual Dysfunctions Including Desire Disorders: What a Provider Needs to Know. Available after September 14, 2010. ABSTRACTS
Taylor M, Pinkett, T, Simon J. Responder Analyses of the Effectiveness of Estradiol Topical Emulsion (ETE) on Hot Flashes. 55th Annual Meeting of the American College of Obstetricians and Gynecologists (ACOG). San Diego, CA. May 5-9, 2007. Simon JA, LaGuardia KD. Extended-release oxybutynin relieves vasomotor symptoms in healthy postmenopausal women. 55th Annual Clinical Meeting of the American College of Obstetricians and Gynecologist (ACOG), San Diego, CA, May 5-9, 2007. Simon J. Nanoparticle Technology: Estrasorb® PK Data Phase III Clinical Trial Data Sunscreen Effects Person to Person Transfer. 10th Annual Meeting of the Nurse Practitioners in Women’s Health (NPWH). Las Vegas, NV. September 27-30, 2007. Simon J. How the Media, the NIH, the WHO and the FDA “Inadvertently Conspired” to Convince Women that Their Hormones Were Dangerous to Their Health. Sociedad Iberoamericana de Osteologia y Metabolismo Mineral (SIBOMM). Santiago, Chile. August 1st – September 2nd, 2007. Simon J. Current Status of the Role of Transdermal Estrogen Therapy: Coagulation and Venous Thrombosis Androgens and Sexual Function Choosing the Patient. 17th Annual Meeting of The North American Menopause Society (NAMS). Dallas, TX. October 3-6, 2007. Simon JA, Komi J. Vulvovaginal Atrophy (VVA) Negatively Impacts Sexual Function, Psychosocial Well-being, and Partner Relationships. The North American Menopause Society (NAMS), Dallas, Texas, October 3-6, 2007. Simon J, Hait H, Reape KZ. Documented Relief of Vulvovaginal Atrophy Symptoms Using a Responder Analysis. 63rd Annual Meeting of the American Society for Reproductive Medicine (ASRM). Washington, D.C. October 13-17, 2007. Simon J, Kingsberg S, Rodenberg C, Schmitt S. Transdermal Testosterone Patch Improves Sexual Function In Surgically Menopausal Women With Hypoactive Sexual Desire Disorder: Results From Two Phase III Clinical Studies, Amsterdam Menopause Society Symposium (AMS), June 19-21, 2007. Simon J, Utian W, Moreau M, Waldbaum A, and Zborowski J. Bio-E-Gel®, A Transdermal Estradiol Gel, Effectively Treats Postmenopausal Vasomotor Symptoms. The Endocrine Society's 89th Annual Meeting of the Endocrine Society. Toronto, Canada. June 2-5, 2007. 10. Simon J. Androgen Co-therapy in the Menopause. The 13th World Congress of Gynecological Endocrinology. Symposium: “Androgens and Androgen Receptors from Bench to Bedside.” Florence, Italy. February 28-March 2, 2008. 11. Simon J, Komi J. Ospemifene, a new SERM, improves the symptoms of vaginal dryness and dyspareunia in postmenopausal women: results from a pivotal Phase 3 study. 12th World Congress on the Menopause. International Menopause Society (IMS). Madrid, Spain. May 19-23, 2008. 12. Simon J. Safety of Androgen Therapy. 12th World Congress on the Menopause. International Menopause Society (IMS). May 19-23, 2008. Madrid, Spain. 13. Simon J. Mazer N, and Wekselman K. Transdermal Testosterone Treatment of Women after Oophorectomy: Safety Profile. 12th World Congress on the Menopause. International Menopause Society (IMS). May 19-23, 2008. Madrid, Spain. 14. Simon J, Nachtigall L, Archer D, Lang E, Gut R, Utian W. An ultra-low dose (10 mcg) Estradiol vaginal tablet is safe and effective for the treatment of vaginal atrophy in post-menopausal women. 18th Annual Meeting of the North American Menopause Society (NAMS), Orlando, FL, September 24-27, 2008. 15. Simon J, Reape K, Hait H. Evaluation of Bleeding Patterns during Twelve Weeks of Treatment with Unopposed Synthetic Conjugated Estrogens-B and Following Progestin Withdrawal. The 18th Annual Meeting of the North American Menopause Society (NAMS). Orlando, Florida. September 24-27, 2008. 16. Simon J. Safety of Androgen Therapy in Women: What do we know? The 13th International Congress on Hormonal Steroids and Hormones and Cancer. Quebec City, Quebec, Canada. September 27-30th 2008. 17. Simon J, Nachtigall L, Archer D, Lang E, Gut R, Utian W. An ultra-low dose (10 mcg) Estradiol vaginal tablet is safe and effective for the treatment of vaginal atrophy in post- menopausal women. 64th Annual Meeting of the American Society for Reproductive Medicine (ASRM) Meeting in San Francisco, CA. November 8-12, 2008. 18. Simon J, Bachmann G, Warren M, Kemp C, Kianifard F, Goncalves J, and Kriegman A. Effect of Zoledronic Acid Compared to Raloxifene on Bone Turnover Markers in Postmenopausal Women with low Bone Mineral Density. 8th International Symposium on Osteoporosis: Translating Research into Clinical Practice. Washington, D.C. April 1-5, 2009. 19. Clark RV, Breed, SL, Dann RS, Simon, JA, Quin W. Efficacy of GSK232801, A Selective Estrogen Receptor Modulator, for Treatment of Vasomotor Symptoms in Healthy Post-Menopausal Women. The Endocrine Society’s 91st Annual Meeting. June 10-13, 2009. Washington, D.C. June 10-13, 2009. 20. Siris E, Silverman S, Viswanathan H, Qian Y, Ragi-Eis S, Fardellone P, Gilchrist N, Lips P, Nevitt M, Palacios S, Pavelka K, Revicki D, Simon J, and Macarios D. Evaluation of Health-Related Quality of Life in Postmenopausal Women Who Participated in the FREEDOM Trial. The American Society for Bone and Mineral Research (ASBMR) 31st Annual Meeting. Denver, CO. September 11-15, 2009. 21. Silverman S, Viswanathan H, Yang, Y, Eis SR, Fardellone P, Gilchrist N, Lips P, Nevitt M, Palacios S, Revicki D, Simon J, Macarios D, and Siris E. Relationships Between Presence, Severity, and Location of Prevalent Vertedbral Fractures and Health Related Quality of Life (HRQoL). American College of Rheumatology 73rd Annual Scientific Meeting. Philadelphia, PA. October 16-21, 2009. 22. Denker AE, Simon JA, Lazarus N, He W, Nelsen L, Gottesdiener K, and Wagner JA. Raloxifene's Effects on Hot Flashes in Healthy Postmenopausal Women: Results of a Randomized Placebo- and Active-Controlled Study. 20th Annual Meeting of the North American Menopause Society (NAMS). San Diego, CA. September 30-October 3, 2009. 23. Thorp J, Dattani D, Taylor L, Simon J, Lesko L, T Kimura, Pyke R. Efficacy of Flibanserin as a Potential Treatment for Hypoactive Sexual Desire Disorder in North American Premenopausal Women: Results from the Daisy Trial. 12th Congress of European Society for Sexual Medicine. Lyon, France. November 15-18, 2009. 24. Simon JA and Mackowiak JI. “Real-World” Patient Experience with Estradiol Gel (EstroGel® 0.06%) Confirms Clinical Trial Efficacy and Patient Satisfaction. 20th Annual Meeting of the North American Menopause Society (NAMS)+. San Diego, CA. September 30-October 3, 2009. 25. Sand M, Thorp J, Simon J, Dattani D, Taylor L, Lesko L, Kimura T, Pyke R. Efficacy of Flibanserin in North American Premenopausal Women with Hypoactive Sexual Desire Disorder: Results from the DAISY trial. Sexual Medicine Society of North American (SMSNA) 2009 Fall Scientific Meeting. November 19 - 21, 2009. San Diego, California. 26. Nachtigall L, Casson P, Lucas J, Schofield V, Melson C, Simon JA. The Safety and Tolerability of the Transdermal Testosterone Patch for Up to 4 Years in Surgically menopausal Women on Estrogen/Progestin Therapy. International Society for the Study of Women’s Sexual Health (ISSWSH) 2010 Annual Meeting. February 18 - 21, 2010. St. Petersburg, FL. (Submitted) 27. Silverman S, Viswanathan H, Qian Y, Ragi-Eis S, Fardellone P, Gilchrist N, Lips P, Nevitt M, Palacios S, Pavelka K, Revicki D, Simon J, Macarios D, Siris E. Evaluation of Health-Related Quality of Life in Postmenopausal Women With Osteoporosis Who Participated in the FREEDOM Trial. International Osteoporosis Foundation (IOF) World Congress on Osteoporosis & 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis 2010 (IOF ECCEO 2010); May 5-8, 2010, Florence, Italy (Submitted). INVITED LECTURES

(Grand Rounds, Visiting Professorships, Memorial Lectures, Workshops, Community
Service, etc.)

2007

Kendig S, Hendrix S, Rossouw J, and Simon J. Moderated by Pearson C. Hormone Replacement
Therapy. A Panel for the National Consumers League and the American Nurses Association.
Women’s Health Forum-Communicating Health Information. National Press Club. Washington,
DC. January 18, 2007.
Simon JA. CBI’s Registries and Post-Approval Studies Congress. Strategies for Success
Investigator Recruitment. January 19, 2007, Tyson’s Corner, Virginia.
Simon J. Biologically Identical Hormone Therapy: Fantasy or Reality. Annual Meeting of the
International Society for the study of Women’s Sexual Health (ISSWSH). February 22-25, 2007.
Lake Buena Vista, FL.
Simon J. Estrogens and Progestogens: Benefits, Impact on Sexual Function, and Risks. Annual
Meeting of the International Society for the study of Women’s Sexual Health (ISSWSH).
February 22-25, 2007. Lake Buena Vista, FL.
Simon J. “The ruling of the EMEA approving testosterone for some women with FSD will have
significant impact for women with FSD worldwide.” A Debate. International Society for the
Study of Women’s Sexual Health (ISSWSH). February 24, 2007. Lake Buena Vista, FL.
Simon J. Chairman Hormone Education Council. Meeting, Webcast, and Video. Philadelphia,
PA. February 10, 2007.
Simon J. Menopausal HT: Menopausal HT: A Look at Current Trial Data. 10th Annual Meeting
of the Society of Nurse Practitioners in Women’s Health (NPWH). Las Vegas, Nevada. April 8,
2007.
Simon J. Effective Management of Postmenopausal Hot Flashes, Sleep, and Sex. 55th Annual
Clinical Meeting of the American College of Obstetricians and Gynecologists (ACOG). San
Diego, CA. May 5-9, 2007.
Simon J. Osteoporosis Consequences: Current Approaches and Challenges to Management of
Osteoporosis. The 55th Annual Clinical Meeting of the American College of Obstetricians and
Gynecologists (ACOG). San Diego, CA. May 5-9, 2007.
Simon J. The postmenopausal women: Unique challenges in the management of low bone mass
and osteoporosis. The 55th Annual Clinical Meeting of the American College of Obstetricians
and Gynecologists (ACOG). San Diego, CA. May 5-9, 2007.
Simon J. The Systemic HT (EPT) Market in the US: Personal Reflections on the Impact of the
Media. 55th Annual Clinical Meeting of the American College of Obstetricians and
Gynecologists (ACOG). San Diego, CA. May 5-9, 2007.
Simon J. Osteoporosis: A view from the Gynecologist’s/Reproductive Endocrinologist’s
Perspective. The Mayo Clinic. Rochester, Minnesota. May 15, 2007.
Simon J. Lies, Damn Lies, and Statistics: The Fact and the Fantasy of the Hormone Therapy
Fiasco. 7th Congress of the Sociedad Iberoamericana de Osteologia y Metabolismo (SIBOMM).
Santiago, Chile. August 29th – September 1st, 2007.
Simon, JA. Critical Evaluation of Androgen Therapy for Low Sexual Desire in Postmenopausal
Women: What is the Evidence?” Mid-Atlantic Chapter of American Association of Clinical
Endocrinologists (AACE) Fifth Annual Meeting & Symposium. Arlington, VA. September 28-
29, 2007.
Female Hypoactive Sexual Desire Disorder (HSDD) in Menopause Women: The Role of
Androgen Therapy. Mid-Atlantic Chapter of American Association of Clinical Endocrinologists
(AACE) Fifth Annual Meeting & Symposium. Arlington, VA. September 28-29, 2007.
Simon JA. Selecting patients for transdermal hormone therapy. The 18th Annual Meeting of The
North American Menopause Society (NAMS). October 3-6, 2007, Dallas, TX; 13-6.
Simon, JA. Fracture Prevention in the Postmenopausal Woman: Focus on Preventing the First
Fracture. Women’s Health Event. Iberia. Sevilla, Spain. November 23-25, 2007.
2008
ParagardT 380A Intrauterine Copper Contraceptive Insertion Training. Nassau University
Medical Center, East Meadow, NY. January 8, 2008.
Simon J. “Menopausal Hormonse Therapy Beyond the Media Hype: So Where are We?” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon J. “Treatment of the Osteopenic/Osteoporotic Patient: Selecting the Most Appropriate Therapy.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon J. “Infertility for the Generalist: How Far Should I Go?” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon J. “Female Sexual Dysfunction and Its Therapy: An Approach for the Primary Care Setting.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon J. “Over – and Under – Treatment of Osteoporosis: Avoiding DXA Pitfalls.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon J. “Maximizing Hormone Therapy: A Multi-Organ System Approach.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon J. “Update on Contraception 2008.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 17-19, 2008. Simon JA. Efficacy and safety of testosterone therapy. Annual Meeting of the International Society of the Study of Women’s Sexual Health (ISSWSH): Testosterone for female sexual dysfunction: How viable? How available? San Diego, CA, February 21, 2008. Simon J. "Testosterone Therapy for Enhancement of Sexual Energy in Menopausal Women: Should Scientists or Politicians Decide?" The 13th World Congress of the International Society of Gynecological Endocrinology. Florence, Italy. February 28-March 2, 2008. Simon J. A fresh look at hormone therapy: Toward a clearer understanding of menopause and
hormone therapy. 75th Annual Conference of the American College of Osteopathic
Obstetricians & Gynecologists (ACOOG), Grand Cypress, FL, March 28, 2008.
Simon J. Female Sexual Dysfunction and its Therapy: Pearls and Pitfalls. 16th Annual Congress
on Women’s Health. Williamsburg, VA. March 28-30, 2008.
Paragard T380A Intrauterine Copper Contraceptive Insertion Training. North Shore University
Hospital, Manhasset, NY. April 16, 2008.
Simon J, and Taylor, M. Bioidentical Hormones: Clinical and Regulatory Realities. The 56th
Annual Meeting of the American College of Obstetricians and Gynecologists (ACOG). New
Orleans, LA. May 3-7, 2008.
Simon J. Biochemical Markers of Bone Remodeling: What are They? How Can They Help Me
in My Clinical Practice? The 56th Annual Meeting of the American College of Obstetricians and
Gynecologists (ACOG). New Orleans, LA. May 3-7, 2008.
Simon J. Hormone Testing & “BioIdentical” Hormones Overview and Definitions. The 56th
Annual Meeting of the American College of Obstetricians and Gynecologists (ACOG). New
Orleans, LA. May 3-7, 2008.
Simon J. Safety of Androgen Therapy in Women: What Do We Know? The 12th World
Congress on the Menopause, International Menopause Society (IMS). May 19-23, 2008. Madrid,
Spain.
Simon J. Androgen Therapy in the Menopause: An Eye Toward Breast Safety. Breast Oncology
Conference. Washington Hospital Center. June 25, 2008.
Simon J. Testosterone Therapy for Enhancement of Sexual Energy in Menopausal Women:
Should Scientists or Politicians Decide? International Public Health. Host: Maxine Weinstein.
Georgetown University. Washington, D.C. 2008.
1st Puerto Rican Symposium about Menopause: The Puerto Rican Menopause Society. San Juan,
PR. September 9, 2008.
Simon J. "Low Dose Transdermal Estradiol Gel for Treatment of Symptomatic Postmenopausal
Women". Roundtable Discussion for the 64th Annual Meeting of the American Society for
Reproductive Medicine (ASRM) Meeting in San Francisco, CA. November 8-12, 2008.
2009
Simon J. “Menopausal Hormone Therapy Beyond the Media Hype: So Where Are We?”
National Institute of Standards and Technology Chapter and NIST Committee for Women. The
Scientific Research Society, SIGMA XI. Gaithersburg, MD. January 15, 2009.
Simon J. “Hypoactive Sexual Desire Disorder (HSDD): Diagnosis and Treatment”. Christiana Care Department of Obstetrics and Gynecology. (Hosts: Drs. Richard Derman and Patricia Carney). Newark, DE. January 28, 2009. Simon J. “Menopausal Hormonse Therapy Beyond the Media Hype: So Where are We?” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 22-24, 2009. Simon J. “Infertility for the Generalist: How Far Should I Go?” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 22-24, 2009. Simon J. “Female Sexual Dysfunction and Its Therapy: An Approach for the Primary Care Setting.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 22-24, 2009. Simon J. “Treament of the Osteopenic/Osteoporotic Patient: Selecting the Most Appropriate Therapy.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 22-24, 2009. Simon J. “Maximizing Hormone Therapy: A Multi-Organ System Approach.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 22-24, 2009. Simon J. “Update on Contraception 2009.” Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class CME. Lake Buena Vista, FL. February 22-24, 2009. Simon J. Debate: “Practical management of HSDD” (Manejo Prático Del Trastorno Del Deseo Sexual Hipoactivo). DIATROS Course. Barcelona, Spain. March 25, 2009. Simon J. “Identifying patients at risk and prevention of fracture”. DIATROS Course. Barcelona, Spain. March 26, 2009. Simon J. “Menopausal Hormone Therapy Beyond the Media Hype: So Where Are We?” Texas Health Presbyterian Hospital. Host: Russell Poland, Ph.D. Dallas, TX. April 14, 2009. Simon J. Satellite Symposium – “Female Sexual Dysfunction (FSD) in the OB/GYN Practice”. ACOG 2009 Annual Clinical Meeting. Chicago, IL. May 3-6, 2009. Pollycove, R and Simon, JA. “Menopause’s Biologic Constraint: Teleologic Origins”. Workshop
on Reproductive Aging. Center for Population and Health, Georgetown University. Washington,
D.C. June 5, 2009.
Simon J. Terapia hormonal: más allá de la exageración de los medios (Hormone Therapy:
Beyond the Media Hype). The Chilean Menopause Society. Santiago, Chile. June 25-28, 2009.
Simon J. Androgenos más allá de la sexualidad: Efectos en hueso, composición corporal,
cerebro y mama (Androgen Therapy: Effects on bones, body composition, brain and breast). The
Chilean Menopause Society. Santiago, Chile. June 25-28, 2009.
Simon J. Treatment of the Osteopenic/Osteoporotic Patient: Selecting the Most Appropriate
Therapy. The Chilean Menopause Society. Santiago, Chile. June 25-28, 2009.
“What’s Your Specialty?: What it means to be a reproductive endocrinologist”. Georgetown
Leadership Youth Forum. Washington, D.C. July 2, 2009.
2010
“Pelvic Floor Dysfunction: Integrating Biofeedback Into Your Practice.” Steven Goldstein and
James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course
Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class
CME. New York City, NY. February 13-15, 2010.
“Maximizing Systemic and Local Hormonal Therapy: A Multi-Organ System Approach.” Steven
Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century
Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and
Gynecologist & World Class CME. New York City, NY. February 13-15, 2010.

“Female Sexual Dysfunction and Its Therapy: An Approach for the Primary Care Setting.”
Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century
Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and
Gynecologist & World Class CME. New York City, NY. February 13-15, 2010.
“Treatment of the Osteopenic/Osteoporotic Patient: Selecting the Most Appropriate Therapy.”
Steven Goldstein and James A. Simon, MD course directors. Survival Skills for the 21st Century
Gynecologist: Course Jointly Sponsored by The American College of Obstetricians and
Gynecologist & World Class CME. New York City, NY. February 13-15, 2010.
“Infertility for the Generalist: Evaluating Ovarian Follicular Reserve”. Steven Goldstein and
James A. Simon, MD course directors. Survival Skills for the 21st Century Gynecologist: Course
Jointly Sponsored by The American College of Obstetricians and Gynecologist & World Class
CME. New York City, NY. February 13-15, 2010.
“Contraception 2010: What’s New and Different.” Steven Goldstein and James A. Simon, MD
course directors. Survival Skills for the 21st Century Gynecologist: Course Jointly Sponsored by
The American College of Obstetricians and Gynecologist & World Class CME. New York City,
NY. February 13-15, 2010.

Source: http://www.whrc.net/uploaded_forms/publicationsJAS2007to2010_021610.pdf

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Advance Access Publication 6 October 2004 Original Article Ozone Therapy on Cerebral Blood Flow: A Preliminary Report Bernardino Clavo1,2,7, Luis Catalá3,7, Juan L. Pérez2,4,7, Victor Rodríguez5 and Francisco Robaina2,6,7 Departments of 1Radiation Oncology and 2Research Unit, 3Radiology, 4Medical Physics and 6Chronic Pain Unit,Dr Negrín Hospital, 5La Paterna Medical Center and 7Canary

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International Political Economy- IPE-studies the political battle between thewinners and losers of global economic exchange. It examines how this politicalshapes the evolution of the international trade and monetary systemsaffects the ability of Multinational Companies ÿ (MNCs)to conductinfluences the development strategies governments adopt.38Thus, IPE suggests that it is hard to understand

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