Solacebiotech.in

Anti-diabetic Products
Product
Composition
Packin
Category
g
Glymon – G1 Bilayered
Anti-diabetic
Glymon – G2 Bilayered
Anti-diabetic
DESCRIPTION:
Glimepiride
The primary mechanism of action of glimepiride in lowering blood glucose appears to be dependent on
stimulating the release of insulin from functioning pancreatic beta cel s. In addition, extrapancreatic effects
may also play a role in the activity of sulphonylureas such as glimepiride.
Metformin
Metformin is an oral antihyperglyacemic drug used in the management of type 2 diabetes. It improves
glucose tolerance in patients with type 2 diabetes (NIDDM).
Metformin improves glucose tolerance in patients with type 2 diabetes (NIDDM),Metformin decreases hepatic glucose production,decreases intestinal absorption of glucose, improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
COMPOSITION
Glymon-G1
Each tablet contains Glimepiride……………….………………………………………….1 mg Metformin Hydrochloride extended-release………………….500 mg Glymon-G2
Each tablet contains
Glimepiride………………. ………………………………………….2 mg Metformin Hydrochloride extended-release ………………….500 mg Indications
GLYMON G1 is indicated as an adjunct to diet and exercise to improve glycaemic control in patients with
type 2 diabetes who are already treated with a combination of glimepiride and metformin or whose
diabetes is not adequately control ed with metformin alone, or for those patients who have initial y
responded to glimepiride alone and require additional glycaemic control.
Dosage And Administration:
General Dosage should be individualized on the basis of both effectiveness and tolerance. The combination should be given once daily with meals and should be started at a low dose. The initial recommended dose is one tablet once daily with breakfast or first main meal of the day.
Based on the usual starting dose of glimepiride (1-2 mg daily), GLYMON G1 or GLYMON G2 may be
initiated once daily, and gradual y titrated after assessing adequacy of therapeutic response.
Based on the usual starting doses of metformin extended release (500 mg once daily), GLYMON G1
or GLYMON G2 may be initiated once daily, and gradual y titrated after assessing adequacy of
therapeutic response .
GLYMON G1 or GLYMON G2 may be initiated based on the dose of glimepirde and metformin already
being taken.
Maximum Recommended Dose:
The maximum recommended dose for glimiperide is 8 mg daily. The maximum recommended daily dose for metformin is 2550 mg in adults.
Contraindications:
Known hypersensitivity to this product or any of its components.
PACKAGING INFORMATION
Glymon-G1.Strip of 10 tablets
Glymon-G2 .Strip of 10 tablets

Source: http://www.solacebiotech.in/other-files/anti-diabetic.pdf