Copy of msds of phorate 10 g- 16 09 08.xls

FORMULATION DIVISION
242/P, GIDC ESTATE, PANOLI - 394 116.
TEL. : (02646)- 645843/46/47/48/53/56FAX. : (02646) - 272213, 272255.
MATERIAL SAFETY DATA SHEET
PAGE NO :1 OF 5
SECTION -1 : MATERIAL IDENTIFICATION & USE
MATERIAL NAME / IDENTIFIER : PHORATE 10 G.
Manufacture's Name :
Supplier's Name :
CHEMINOVA INDIA LIMITED.
CHEMINOVA INDIA LIMITED.
Street Address :
Street Address :
242/P GIDC. PANOLI . Gujarat(INDIA).
242/P GIDC. PANOLI. Gujarat(INDIA).
City : PANOLI (ANKLESHWAR).
City : PANOLI (ANKLESHWAR).
Postal Code :
Postal Code :
Emergency Telephone :
Emergency Telephone :
(0091)2646- 645843/46/47/53/56/57
(0091)2646- 645843/46/47/53/56/57
Chemical Name:PHOSPHORODITHOIC ACID.
Chemical Identity : Insecticide
methyl-2-(methylcarbamoyl)-vinyl phosphate.
Trade Name & Synonyms : PHORATE 10 G
Product Use : Agricultural use as
Insecticide.
SECTION -II : HAZARDOUS INGREDIENT OF MATERIAL
Hazardous
Approximate
LD 50 ( species
LC50 (specify
Ingredients
concentration %
& route)
species & tests)
1. Phorate
298-02-2
Toxicity for rat
active ingradient
Oral LD 50 of
1 Hrs. Inhalation
Technical grade
LC 50 of Technical
pesticide
pesticide
dermal 99 mg/kg
2.Other ingradient
SECTION - III:COMPONENTS AND CONTAMINANTS
COMPONENT: PHORATE PERCENT: 10
CAS # 298-02-2
EXPOSURE LIMITS :PHORATE:0.05 mg/m3 OSHA TWA(Skin),0.2 mg/m3 OSHA STEL,0.05 mg/m3
ACGIH TWA (Skin),0.2 mg/m3 ACGIH STEL.
SECTION - IV : PHYSICAL DATA FOR MATERIAL
Physical state
Specific gravity
Solid/liquid/Gas
Appearance
Threshold(ppm)
Strong mercaptan
Vapour Pressure
Vapour Density
Evaporation Rate
Boiling Point
Freezing Point
Solubility in water
Density (gm/ml)
Coefficient of
(1% aq.solution)
7.29 at 25°C
oil distribution
FORMULATION DIVISION
242/P, GIDC ESTATE, PANOLI - 394 116.
TEL. : (02646)- 645843/46/47/48/53/56FAX. : (02646) - 272213, 272255.
PAGE NO :2 OF 5
SECTION - V : FIRE AND EXPLOSION HAZARD OF MATERIAL
Fire and Explosion Hazard : Slight fire hazard when exposed to heat or flame.
Flash Point : Not Applicable Flammability Class :
Firefighting Media:Dry chemical, Carbon dioxide, halon, water spray or standard foam for larger fires,
use water spray fog or standard foam.
Firefighting : Move containers from fire area if possible.Extinguish using agent suitable for type of
surrounding fire.Avoid breathing vapors and dust. Keep up wind.
SECTION - V I : REACTIVITY DATA
Chemical Stability : Stable under normal temperatures and pressures.
Incompatibility :PHORATE:Oxidizers(strong):Fire and explosion hazard.
Decomposition : Thermal decomposition product may include toxic oxides of carbon,sulfur,and
phosphorus.
Polymerization : Hazardous polymerization has not been reported to occur under normal temperatures
and pressures.
SECTION - VI I : TOXICOLOGICAL PROPERTIES OF MATERIAL
PHORATE Tech grade pesticide:Toxicity Data:11 mg/m3/1 hour inhalation-rat LC 50;99 mg/kg skin-Rabbit
LD 50;2500 ug/kg Skin-Rat LD 50;20 mg/kg Skin-Guinea pig LD 50;1 mg/kg Oral-Rat LD 50; 6590 ug/kg
Oral-Mouse LD 50; 1200 ug/kg Intravenouus-Rat LD 50;1866 ug/kg Intraperitoneal-Gerbil LD 50;
Mutagenic data (rtecs).Reproductive effects Data:Carcinogen status: None. Acute toxicity level : Highly
toxic by inhalation dermal absorption,ingestion.Target effects: Cholinesterase inhibitor.Poisoning may
affect the nervous system.At increased risk from exposure: Persons with respiratory ailments,recent
exposure to cholinestrease inhibitors or Impaired cholinesterase production,or liver malfunction.
Additional data:May cross the placenta.High environmental temperatures or exposure of the chemical
to visible or ultraviolet light may enhance the toxicity.Intractions with medications may occur.
SECTION - VIII : PREVENTIVE MEASURES
Personal protective equipments :
Gloves (specify)
Respiratory (specify)
Eye (specify)
Neoprene & PVC handgloves
Fume mask,air respirator
Safety goggles / Face Shield
Disposible handgloves
Footware (specify)
Clothing (specify)
Others (specify) or
Gumboots / Safety glass
Apron, long pent, full sleeve shi Face shield / helmet or cap.
head covering.
Fume mask , cotton mask.
Engineering controls :
( e.g. ventilation,enclosed process etc.) specify also.
(1)Suction system with suction hood at all emission/open exposure points,connected to scrubber by
ducting line is provided.
(2)Fresh air supply system with ducting lines along all the packing lines and charging area points.
(3)Sufficient number of exhaust fans,wall mounted fresh air fans,Air respirator are provided in the
production area.
Leak & spill containment procedures recommended :
Clay / saw dust is spreaded onspilled material,spilled material is allowed to absorb.Absorbe
material collected in bin for safe disposar.
Waste disposal procedures recommended :
Procedure:(1)Ensure technical drums are empty.(2)Empty drums of technicals to be decontamination
with diluted caustic solution,then flushed with water.(3)Shift the decontaminated drum for cutting and
puncturing where cutting eqipment device of drums is installed.(4)The top and bottom lid of detoxified
drums is seperated.(5) The detoxified drum centre portion is cut horizontally.(6)The M.S.sheet is then
disposed through the approved vender.
Handling procedures & equipment :
Self priming pump,barrel pump,drum lifter cum tilter,and centrifugal pump through material is
transfered in close condition through pipe line to avoid emission of vapor using equipment line.
Storage requirements :
Store in ventilated finished goods godown , with adaquate number of fire extinguisher.
FORMULATION DIVISION
242/P, GIDC ESTATE, PANOLI - 394 116.
TEL. : (02646)- 645843/46/47/48/53/56FAX. : (02646) - 272213, 272255.
PAGE NO :3 OF 5
SECTION - IX : HEALTH EFFECTS AND FIRST AID
INHALATION : Phorat technical grade pesticide - Highly toxic.
Organophosphates:Cholinesterase inhibitor.Acute Exposure-when inhaled, the first effects of
cholinesterase inhibitors are usually respiratory and may include nasal hyperemia and watery
cough,chest discomfort,dyspnea and wheezing due to increased bronchial secretions and
bronchoconstriction.If sufficient amounts are absorbed,other systemic effects may begin within a few
few minutes or be delayed for up to 12 hours. Symptoms may include pallor,nausea,vomiting,diarrhea,
abdominal cramps, headache, dizziness, ocular pain , blurred vision,miosis or in some cases,especially
initially mydrisis,lacrimation,salivation,sweating,and confusion.Other reported central nervous system or
neuromuscular effects may include ataxia, slurrd speech,areflexia,weakness,fatigue,fasciculation,
twitching,tremors possibly of the tongue and eyelid,and eventually paralysis of the extermities and
possible of the respiratory muscles.In severe cases there may also be involuntary defection and urition,
cynosis,psychosis,hyperglcemia,acute pancretitis,cardac irrgularties,pulmonary edema,unconsciousness,
convulsions, and coma. Death ispremarily due to respiratory failure, although cardiovascular effects
including cardiac arrest may also be implicated.Long term secquelae are rare but may include
neuropsychiatric disorders and myopathy with muscle tenderness.
CHRONIC EXPOSURE : Repeated or prolonged exposure may results in the effects of acute exposure
including the delay of neuropathy.Other effects reported in workers repeatedly exposed include
impaired memory and concentration,acute psychosis, severe depressions,irritability,confusion,apathy,
emotional lability,social withdrawal,confusion,headche,speech difficulties,delayed reaction times,
spatial disorientation,Nightmares,sleep walking,and drowiness or isomnia.An influenza-like condition
with headache, nausea, weakness,anorexia, and malaise has also been reported.
FIRST AID - Remove from exposure area to fresh air immediately. If breathing has stopped, Give
artificial respiration.Maintain airway and blood pressure and administer oxygen should be performed
by qualified personnel.Get medical attetion immediately.
SKIN CONTACT: Phorate technical grade pesticide:Highly toxic.
ORGANOPHOSPHATES: Absorption through the skin is so rapid that death has occurred in animals
within an 1-2 hours of contact.
ORGANOPHOSPHATES:Cholinesterase inhibitor.
ACUTE EXPOSURE: Localized sweating and fasciculations may occur at the site of contact.If sufficient
amounts are absorbed, other effects of cholinesterase inhibition as described in acute inhalation may
occur. Symptoms may be delayed 2-3 hours, but usually no more than 12 hours. The rate of absorption
is incrased by the presence of dermatitis or high ambient temperatures.Delayed neuropathy is also
possible.
CHRONIC EXPOSURE : Repeated or prolonged exposure may cause effects as described in acute
exposure.Some organophosphates may cause sensitization.
FIRST AID.remove conminated clothing immediately. Wash contaminated areas with soap and water
followed by alcohol.Emergency personnel should wear gloves and avoid contamination.Treat
respiratory difficulty with artificial respiration.Get medical attention immediately.
EYE CONTACT: Phorate technical grade pesticide: Highly toxic.
ORGANOPHOSPHATES. Cholinesterase inhibitor.
ACUTE EXPOSURE: Direct contact may cause pain,hyperemia,lacrimation,twitching, of the eyelid,miosis
and ciliary muscle spasm with loss of accomodation,blurred or dimmed vision and browache.Sometimes
mydriasis may occur instead of miosis.With sufficient exposure,other symptoms of cholinesterase
inhibition as discribed in acute inhalation may occur.
CHRONIC EXPOSURE: Repeated or prolonged exposure may cause effects as described in acute
exposure.Some compounds have caused toxic obstruction of the nasolacrimal canals when used as
miotic eyedrops.
FIRST AID-Irrigate eyes with water or saline solution.If symptoms of poisoning occur,treat respiratory
difficulty with artificial respiration and oxygen. Observe patient for at least 24-36 hours. Get medical
attention immediately.Oxygen should be administered by qualified medical personnel.
INGESTION : Phorate technical grade pesticide : Highly toxic.
ORGANOPHOPHATES : Cholinesterase inhibitor.
ACUTE EXPOSURE : When ingested, the first effects may be nausea,vomiting,anorexia,abdominal
cramps and diarrhea.Gastrointestinal absorption may cause symptoms of cholinesterase inhibition as
described in acute inhalation.Symptoms may begin within minutes or be delayed for hours.Delayed
effects including neuropathy may also occur.
FORMULATION DIVISION
242/P, GIDC ESTATE, PANOLI - 394 116.
TEL. : (02646)- 645843/46/47/48/53/56FAX. : (02646) - 272213, 272255.
PAGE NO :4 OF 5
CHRONIC EXPOSURE : Repeated ingestion may cause effects as described in acute exposure.
FIRST AID:If person is alret and respiration is not depressed, give syrup of ipecac followed by water ( if
vomiting occurs,keep head below hips to prevent aspiration).If consciousness level declines or vomiting
has not occurred in 15 minutes empty stomach by gastric lavage with the aid of cuffed endotrachel tube
using isotonic saline or 5% sodium bicarbonate follow with activated charcol.Establish and maintain
airway.Treat respiratory difficulty with artificial respiration and oxygen.Do not give morphine,
aminophylline,phenothiazines,reserpine,furosemide,or ethacrynic acid.Treat symptomatically and
supportively.Administration of oxygen and lavage must be performed by qualified medical personnel.
Get medical attention immediately.
SECTION - X : ANTIDOTE
The following antidote(s) have been recommended. However the decision as to whether the severity of
poisoning requires administration of any antidote and actual dose required should be made by qualified
medical personnel.For cholinesterase inhibitors: Establish clear airway and tissue oxygenation by
aspiration of secretions,and if necessary by assisted pulmonary ventilation with oxygen.Improve tissue
oxygenation as much as possible before administering atropine to minimize the risk of verticular
fibrillation.Administer atropine sulfate intravenously,or intramusculary if iv injection is not possible.In
moderately severe poisoning administer atropine sulfate 0.4 - 2.0mg repeated every 15 minutes until
atropinization is achived (Tachycardia, flushing,dry mouth,mydriasis). Miantain atropinization by
repeated doses 2-12 hours,or longer,depending on the severity of poisoning.The appearance of rales in
the lung bases,miosis,salivation nausea,bradycardia,are all indications of inadequate atropinization.
Severly poisoned individuals may exhibit remarkable tolerance to atropine;two or more times the
dosages suggested above may be needed.Persons not poisoned or only slightly poisoned,However,may
may develop signs of atropine toxicity from such large dosages: Fever,muscle fibrillation,and delirium
are the main signs of atropine toxicity.If these signs appear while the patient is fully atropinized,atropine
administration should be discontinued, atleast temporarly.Observe treated patients closely at least 24
hours to insure that symptoms (possible pulmonary edema).Do not recur as atropinization wears off.In
very severe poisonings, metabiolic disposition of toxycant may require several hours or days during
which atropinization must be maintained.Markedly lower levels of urinary metabolites indicate that
atropine dosage can be tapered off.As dosage is reduced,check the lung bases frequently for rales.If
rales are heard or other symptoms return,re-establish atropinization promptly.Administeration of
antidote must be performed by qualified medical personnel.
In case of sever poisoning by organophosphate pesticides in which respiratory depression, muscle
weakness and twitching are severe,give pralidoxime(protopam-ayerst,2-PAM),1.0 gram intravenously at
no more than o.5 gram per minute.Dosage of pralidoxime may be repeated in 1-2 hours,that at 10-12
hour intervals if needed.In very severe poisonings,dosage rates may be doubled.Treatment with
pralidoxime will be most effective if given within thirty-six hours after poisoning.Antidote should be
administered by qualified medical personnel.
SECTION- XI : CONDITIONS TO AVOID
May burn but does not ignite readily.
SECTION- XII : SPILL AND LEAK PROCEDURES.
OCUPATIONAL SPILL :Do not touch spilled material. Stop leak if you can do it without risk. Use water
spray to reduce vapors.For small spills,take up with sand or other absorbent material and place into
containers for later disposal.For small dry spills,with a clean shovel place material in to clean,dry
containers and cover. Move containers from spill area.For larger spills,Dike far ahed of spill for later
disposal.Keep unnecessary people away. Isolate hazard area and deny entry.Ventilate closed spaces
before entering.
FORMULATION DIVISION
242/P, GIDC ESTATE, PANOLI - 394 116.
TEL. : (02646)- 645843/46/47/48/53/56FAX. : (02646) - 272213, 272255.
PAGE NO :5 OF 5
SECTION-XIII : PROTECTIVE EQUIPMENT
VENTILATION :
(1)Suction system with suction hood at all emission/open exposure points,connected to scrubber by
ducting line is provided.
(2)Fresh air supply system with ducting lines along all the packing lines and charging area points.
(3)Sufficient number of exhaust fans,wall mounted fresh air fans,Air respirator are provided in the
production area.
RESPIRATOR : The following respirators are recommended based on information found in the physical
data,toxicity and health effects sections. They are ranked in order from minimum to maximum
respiratory protection.The specific respirator selected must be based on contamination levels found in
the work place.
For firefighting and other immediately dangerous to life or health condition :
Self-contained breathing apparatus with full facepiece operated in pressure-demand or other positive
pressure mode,supplied-air respirator with full facepiece and operated in pressure-demand or other
positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in
pressure-demand or other positive pressure mode.
CLOTHING : Employee must wear appropriate protective (Impervious) clothing and equipment to
prevent any possibility of skin contact with this substance.
GLOVES : Employee must wear appropriate protective gloves to prevent contact with this substance.
EYE PROTECTION:Employee must wear splash-proof or dust-resistant safety goggles and a faceshield to
prevent contact with this substance.
Emergency wash facilities : Where there is any possibility that an employees eye and/or skin may be
exposed to this substance, the employer should provide an eye wash fountain and quick drench shower
within the immediate work area for emergency use.
SECTION-XIV : STORAGE AND DISPOSAL
* *STORAGE **
(1) The packages containing the insecticides shall be stored in separate rooms or premises away from
the room or premises used for storing other articles or shall kept in separate almirahs under lock and
key depending upon the quantity and nature of the insecticides.
(2) The room or premises ment for storing the inceticides shall be well built,dry,well ventilated and of
sufficient dimension to avoid contamination with vapour.
**DISPOSAL**
(1)The leakage/damage packages shall not be left out side to prevent their re-use.
(2)Packages and surplus material and washing should be disposed off in a safe manner so as to prevent
environment or water pollution.
(3)Cartons should be torn,crushed and completely destroyed and then disposed off safely.
(4)Disposible of detoxified plastic bag: Toxic material from empty plastic bags is totally collected.These
empty bags are washed with caustic solution,then with fresh water.These detoxified bags are cut
horizontally and vertically and tide bundeles.It is then disposed through the approved vendors.

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