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September MIMS Monthly Medicine Update
NEW PRODUCTS
Priligy (dapoxetine hydrochloride)
Zaltrap (aflibercept (rch)) is a
Erivedge (vismodegib) is a low
severe chronic neutropenia (SCN); and in endothelial growth factor (VEGF) receptor (1 and 2) extracellular domains fused to HIV therapy. Zarzio is contraindicated in ejaculatory latency time (IELT) of less than patients with known hypersensitivity to E (SMO) leads to the activation and nuclear coli derived products. Zarzio is available localisation of GLI transcription factors ejaculation with minimal sexual stimulation GyMiso is contraindicated in the following before, on, or shortly after penetration microgram per 0.5 mL prefilled syringe.
situations: if there is a contraindication expression system. Zaltrap in combination SAFETY RELATED CHANGES
transduction. Erivedge is indicated for the chemotherapy is indicated in adults with Avapro, Karvea (irbesartan) and
treatment of adult patients with metastatic treatment with anticoagulants; uncertainty a poor control over ejaculation. Priligy Avapro HCT, Karvezide (irbesartan/
is contraindicated in all of the following hydrochlorothiazide) are now
conditions: significant pathological cardiac contraindicated with aliskiren containing surgery and/or radiation therapy are not mifepristone. GyMiso is available as a 200 medicines in patients with diabetes or with appropriate. Erivedge is contraindicated failure), conduction abnormality (2nd, 3rd hyperosmotic properties of Zaltrap. Zaltrap moderate to severe renal impairment.
Jakavi (ruxolitinib phosphate) is an
degree A-V block or sick sinus syndrome) is available in vials of 100 mg/4 mL and Efudix (fluorouracil) is now
inhibitor of the Janus Associated Kinases Zarzio (filgrastim (rbe)) is a
treatment and for 7 months after the last potency. JAKs mediate the signalling of a disease; concomitant MAOIs, thioridazine, dose. It is also contraindicated in nursing Stimulating Factor (rmetHuG-CSF) derived Normison (temazepam) is now
mothers during the course of treatment and drugs/ herbs (eg L-tryptophan, triptans, from E. coli. Zarzio is indicated in the for 7 months after the last dose because of and immune function. Ruxolitinib inhibits tramadol, linezolid, lithium, St John’s reduction of neutropenia duration, clinical the potential to cause serious development JAK-STAT signalling and cell proliferation wort) (including less than 14 days before defects in breastfed infants and children. starting, less than 7 days after ceasing depression, due to a risk of suicide.
Erivedge is available as a 150 mg tablet in Xarelto (rivaroxaban) is now
is indicated for the treatment of disease inhibitors eg ketoconazole, itraconazole, atazanavir, nelfinavir, ritonavir, saquinavir, GyMiso (misoprostol) is a synthetic
mobilisation of peripheral blood progenitor telithromycin, nefazodone; and in moderate analogue of prostaglandin E1. In the event patients with primary myelofibrosis, post- to severe hepatic impairment. Priligy is This list is a summary of only some of the available as a 30 mg tablet is packs of 3’s changes that have occurred over the last essential thrombocythemia myelofibrosis. donors (allergenic); infection incidence month. Before prescribing, always refer to Jakavi is available as 5 mg, 15 mg and 20

Source: http://openthemedicinebox.com/mims/medupdate-2013-09.pdf