I. Basic research period (1996-1986) . 1 III. Publications in the HTA-period (2000-2005) . 6 HTA-lectures and abstracts in recent years, 2000-2006. 7
The present publications list only covers activities in 2 out of 3 of the periods mentioned below: I. Basic research period (1976-1986)
medio1976 - medio 1979 (research during medical studies)
primo 1981 - medio 1986 (senior research fellow)
II. Commerciel research and development (1986-2000) – not available
III. HTA-period (2000-2005)
I. Basic research period (1996-1986) Besides publications in international journals, a doctoral dissertation was prepared ( primo 1981) from publications finalised during the medical study period. The dissertation was accepted and defended 5/11 1982 at Odense University. Title of doctoral dissertation: Purification and quatification of two pregnancy associated alfa-2 mobile serum proteins with special reference to preparative and analytical immunochemical techniques.
Regular publications as first author: 1 Folkersen,J.;Teisner,B.; Svendsen,P. and S.-E. Svehag An Immunoprecipitation-dissociation technique for large scale antibody purification and an antigen consumption electroimmunoassay for antibody quantification. A model study with antibodies to pregnancy zone protein. Journal of Immunological Methods, 23 (1978) 127-135 2 Folkersen,J.;Teisner,B.;Ahrons,S. and S.-E. Svehag Affinity chromatographic purification of the pregnancy zone protein Journal of Immunological Methods, 23 (1978) 117-125 3 Folkersen,J.;Teisner,B.;Westergaard,J.G. and S.-E.Svehag An automatic multi-programmed affinity chromatographic system Journal of Immunological Methods, 23, (1978) 137-147 4 Folkersen,J.;J.G.Westergaard.;Hindersson,P. and B.Teisner
Affinitychromatographic purification of a new high molecular weight pregnancy specific protein - SP-4 Carcinoembryonic proteins, Vol II, Ed, F.G.Lehmann, Elsevier. (1979) 503-508 5 Folkersen,J.;Teisner,B.;Hindersson,P. and S.-E. Svehag A method for preparation of immunosorbents by direct coupling of dissociated immune complexes Journal of Immunological Methods, 32,(1980) 327-338 6 Folkersen,J.;Teisner,B.;Grunnet,N.;Grudzinskas,J.G.;Westergaard,J.G. and P.Hindersson Circulating levels of pregnancy zone protein: Normal range and the influence of age and gender Clinica Chimica Acta, 110 (1981) 139-145 7 Folkersen,J.;Grudzinskas,J.G.;Hindersson,P.;Teisner,B. and J.G.Westergaard Pregnancy associated plasma protein A: Circulating levels during normal pregnancy Am.J.Obstet. Gynecol., 139, (1981) 910-914 8 Folkersen,J.;Grudzinskas,J.G.;Hindersson,P.;Teisner,B. and J.G.Westergaard Purification of pregnancy associated plasma protein A by a two step affinity chromatographic procedure Placenta, 2, (1981) 11-18 9 Folkersen,J.;Hindersson,P.;Svendsen,P.;Teisner,B. and S.-E. Svehag Counter-current -line-immunoelectrophoresis. A new electrophoretic method for analysis of oligospecific antigen-antibody systems. Scandinavian Journal of Immunology, Suppl. No. 10, Vol 17, (1983) 199-203 10 Folkersen,J.; Teisner,B.; Petersen,N.E.; Sim,R.B. and E.Jessen Preparation of antibodies against the fourth complement component (C4) and development of a direct electroimmunoassay for quantification of C4d. J.Clin.Lab.Immunol.,16,(1985) 163-167 11 Folkersen,J.;Sim,R.B.;Sottrup-Jensen,L. and S.-E. Svehag Application of the immunoblotting technique to the study of single protein species in complex biological fluids: A model study with alfa-2-macroglobulin. Electrophoresis, 6, (1985) 227-234 12 Folkersen,J.;Søfeldt.S.; and S.-E.Svehag Application of the electroblotting technique to the studies of the intestinal antibody response to extractable fecal antigens. Scand.J.Gastroenterology, 20, (1985) 247-253 13 Folkersen,J.;Teisner,B.;Westergaard,J.G. and J.G.Grudzinskas The selection of antibodies with defined desorption conditions from precipitated immune complexes for use in immunoadsorption procedures. Journal of Immunological Methods, 77, (1985) 45-54 14 Folkersen,J.;Teisner,B.;Eggertsen,G. and R.B.Sim Immunoblotting analysis of the peptide structure of the physiologic breakdown products of the third component of human complement. Electrophoresis,7,(1986)379-386 Other authorships
15 Teisner,B.;Mogensen,B.;Folkersen,J and S.-E. Svehag Throphoblastic tumour, oral contraceptive therapy and pregnancy associated alpha-2-glycoprotein (PAAG), case report. British Journal of Obstetrics and Gynecology.vol 84, No.8 (1977) 630-632 16 Svendsen,P.;Stigbrand,T.;Teisner,B.;Folkersen,J.;Damber,M.-G.; Von Schoultz,B.; Kemp.E.;and S.-E. Svehag. Immunosuppressive effect of human pregnancy zone protein on H-2 incompatible mouse heart allografts. Acta.Path.Microbiol.Scand. C. 86, (1978) 199-201 17 Teisner,B.;Westergaard,J.G.;Folkersen,J.;Husby,S. and S.-E. Svehag Two pregnancy associated serum proteins with pregnancy specific glycoprotein determinants Am.J. Obstet.Gynecol. Vol 131, No 3, (1978) 262-266 18 Westergaard,J.G.; Folkersen,J.;Hindersson,P.;Svehag,S.-E. and B.Teisner Two serum proteins with SP-1 determinants Carcino-embryonic proteins,Vol II, Ed.F.G.Lehmann, Elsevier.(1979) 463-468 19 Teisner,B.;Folkersen,J.;Hindersson,P.;Jensenius,J.C. and J.G.Westergaard Quantification of the pregnancy specific beta-1-glycoprotein (SP1) by immunoprecipitation techniques: The influence of a crossreacting high molecular weight alfa-2-protein. Scand. J. Immunol., 9, (1979) 409-417 20 Westergaard,J.G.;Teisner,B.;Folkersen,J.;Hindersson,P.;Schultz-Larsen,H. and S.-E Svehag Characterization of two pregnancy associated serum proteins with pregnancy specific beta-1-glycoprotein (PS-beta-G)-determinants. Scand.J.Clin.Lab.Invest., 39, (1979) 351-359 21 Hindersson,P.;Folkersen,J.;Westergaard,J.G.;Teisner,B. and S.-E. Svehag Specific assay for pregnancy specific beta-1-glycoprotein (SP1-beta). Preparation of antiserum specific for SP1-beta by adsorption with a crossreacting high molecular weight serum protein Journal of Reproductive immunology, 1, (1979) 159-166 22 Teisner,B.; Folkersen,J.;Svendsen,P.; Hau,J. and P.Hindersson Demonstration of an analoque to human pregnancy zone protein in the african green monkey Journal of Medical Primatology,8, (1979) 298-304 23 Grudzinskas,J.G.;Teisner,B.;Al-Ani,A.T.M.;Folkersen,J.;Westergaard,J.G. and T. Chard Immunochemical and Biological studies on two molecular variants of pregnancy specific beta-1-glycoprotein (SP-1) SP1-alfa and SP1-beta. Clinica Chimica Acta, 106, (1980) 1-7 24 Westergaard,J.G.;Folkersen,J.; Hindersson,P. and B.Teisner Circulating levels of high molecular weight pregnancy specific protein (SP-4) in normal and pathological pregnancies. In HUMAN PLACENTA: PROTEINS AND HORMONES (Ed. A.Klopper), acad.press, London, 121-128, (1980)
25 Westergaard,J.G.;Sizaret,PH.;Hindersson,P.;Folkersen,J and B.Teisner Pregnancy specific beta-1 glycoprotein (SP1) in patients with throphoblastic disease: Molecular heterogeneity and a "SP1 consuming factor". Acta.Path. Microbiol.Scand. Sect.C, 88, (1980) 233-236 26 Teisner,B,;Grudzinskas,J.G.;Hindersson,P.;Folkersen,J.;Westergaard,J.G. and T. Thard Pregnancy specific beta-1-glycoprotein (SP-1). Molecular heterogeneity and measurement. Serono Symposium No. 35,"The human Placenta" Ed. A.Klopper et al., Acad. Press.(1980) 79-85 27 Hindersson,P.;Teisner,B.;Folkersen,J.;Gruszinskas,J.G. and J.G.Westergaard Investigations into the molecular heterogeneity of pregnancy specific beta-1 glycoprotein (SP1) Placenta, 2, (1981) 233-240 28 Wahlstrøm,T.; Teisner,B. and J.Folkersen Tissue localization of pregnancy associated plasma protein A (PAPP-A) in normal placenta Placenta,2,(1981) 253-258 29 Wahlstrøm,T.;Teisner,B.;Lee,J.-N.;Grudzinskas,J,G.;Zeppala,M. and J.Folkersen Placenta-associated plasma protein-A (PAPP-A, SP-4) in throphoblastic tumours Acta Path. Microbiol.Scand. Sect.C ,89, (1981) 65-66 30 Teisner,B.; Lange,A.P.;Folkersen,J.;Antonsen,H.;Von Schoultz,B, and T.Stigbrand Serum levels of the "pregnancy-zone protein" during short term prenatal dexamethasone therapy. Acta Obstet. Gynecol. Scand. 60, (1981) 161-164 31 Chemnitz,J;Hau,J.;Svendsen,P.;Folkersen,J.Westergaard,J.G. and B.C.Christensen Immunochemical demonstration of human and murine pregnancy associated serum proteins in maternal and placental tissue. Biblioteca Anatomica, 22, (1982) 87-92 32 Sinosich,M.J.; Teisner,B.; Folkersen,J,:Saunders,D.M. and J.G. Grudzinskas Radioimmunoassay for pregnancy associated plasma protein A Clinical Chemistry, 28, (1982) 50-53 33 Hansen,O.;Jensenius,J.C.;Folkersen,J. and I.Brandslund Production of antibodies against C3c epitopes which are inaccessible on native C3. J.Immunological Methods, 61,(1983)245-252 34 Teisner,B.; Hau.J.;Folkersen,J. and H.H.Jepsen Charge and size heterogeneity of C3d following in vivo activation of the complement system Complement, 1,(1984) 36-43 35
Teisner,B.;Brandslund,I.;Folkersen,J.;Rasmussen,J.M.;Poulsen,L.O. and S.-E. Svehag Factor I deficiency and C3 nephritic factor: Immunochemical findings and association with Neisseria meningitidis infection in two patients. Scand.J.Immunol. 20 (1984) 291-297 36 Tornehave,D.; Chemnitz,J.; Teisner,B.;Folkersen,J. and J.G.Westergaard Immunohistochemical demonstration of pregnancy-associated plasma protein A (PAPP-A) in the syncytiothrophoblast of the normal placenta at different gestational ages. Placenta, 5, (1984) 427-432 37 Sottrup-Jensen,L.;Folkersen,J.;Kristensen,T. and B.F.Tack Partial primary structure of human pregnancy zone protein. Extensive sequence homology with human alfa-2 macroglobulin. Proc.Nat.Acad.Sci. USA, 81, (1984) 7353-7357 38 Teisner, B., Petersen, N. E., Folkersen, J. & Hau, J. Crossed immunoelectrophoretic analysis of split products of the third complement factor (C3d) following IN VIVO activation of the complement system. Electrophoresis, 5, 84-87, 1984. 39 Eggertsen,G.;Hellman,U.;Lundwall,Å.;Folkersen,J.and J.Sjøquist. Characterisation of tryptic fragments of human complement factor C3 Molecular Immunology, vol 22,No.8,(1985) 833-841 40 Petersen,N.E.; Folkersen,J.;Teisner,B.; and S.-E. Svehag Immunoelectrophoretic analysis of C4 split products expressing D but not C epitopes: Influence of storage,
Ca2+ and Ca2+-chelating agents. Complement, 2, (1985) 147-155 41 Sand,O.; Folkersen,J.;Westergaard,J.G. and L. Sottrup Jensen Characterisation of Human pregnancy zone protein. Comparison with human alfa-2-macroglobulin. J.Biological Chemistry, Vol.260,No.29 (1985) 15723-15735 42 Carlsson,L.; Folkersen,J. and T. Stigbrand Antigenic determinants of pregnancy-associated alfa-2-glycoprotein and alfa-2-macroglobulin defined by poly- and monoclonal antibodies. Molecular Immunology, Vol.22, No 9, (1985) 1073-1080 43 Tornehave,D.;Folkersen,J.;Teisner,B. and J.Chemnitz Immunohistochemical aspects of immunological crossreaction and masking of epitopes for localization studies on pregnancy-associated plasma protein-A (PAPP-A). Histochem.J.,18, (1986) 184-188 44 Chemnitz,J.;Folkersen,J.;Teisner,B.;Sinosich,M.J.;Tornehave,D.;Westergaard,J.G.;Bolton,A.E. and J.G.Grudzinskas Comparison of different antibody preparations against pregnancy associated plasma protein A (PAPP-A) for use in localization and immunoassy studies. British Journal of Obstetrics and Gynecology, 43, (1986) 916-923 45 Armstrong,N.P.I.;Teisner,B.;Redman,C.W.G.;Westergaard,J.G.;Folkersen,J. and J.G.Grudzinskas
Complement activation, circulating protease-inhibitors and pregnancy associated proteins in severe pre-eclampsia. British Journal of Obstetrics and Gynecology, 93, (1986) 811-814 46 Petersen, N. E., Teisner, B., Folkersen, J. & Svehag, S-E. Heterogeneity of C4d and C3d and their complex formation with serum albumin. Acta Path. Microbiol. Immunol. Scand., Sect. C, 95, 129-135, 1987. 47 Jepsen, H. H., Teisner, B., Folkersen, J., Rasmussen, J. M. & Svehag, S-E. Enhancing effect of autologous human erythrocytes on generation of C3 cleavage products beyond iC3b. Complement, 5, 120-129, 1988. 48 Poulsen, O. M., Hau, J., Teisner, B., Folkersen, J., Westergaard, J. G. Proteolytic activity of human P -fetoprotein. INT. J. FET0-MAT. MED., 1, 131-136, 1988.
III. Publications in the HTA-period (2000-2005)
49 Folkersen J og Holt Petersen P. Holdningsundersøgelse vedrørende anvendelse af mini-medicinsk teknologivurdering før indførelse af nye medicinske teknologier på Rigshospitalet. Ugeskr Læger 2006;168(21):2069 50 Jennum P, Folkersen, J og Andreasen J. Diagnostik og behandling af obstruktiv søvnapnø. En medicinsk teknologivurdering. ISBN 87-7676-312-9. 2006. 6(5). København, Sundhedsstyrelsen. 51 Folkersen J, Andreasen J, Basse L, Jakobsen DH, Kehlet H . Det accelererede kolonkirurgiske patientforløb.En medicinsk teknologivurdering. ISBN 87-7676-232-7. 2005. 5(7). København, Sundhedsstyrelsen 52 Rørbye C, Nilas L, Juul Larsen R, Wallach Kildemoes H og Folkersen J. Medicinsk versus kirurgisk 1. trimester abort. En medicinsk teknologivurdering. ISBN 87-7676-181-9. 2005, 5(6). København, Sundhedsstyrelsen. 53 Lilja Pedersen B, Folkersen J, Wallac Kildemoes H, Kjærgaard H, Mogensen T, Ottesen B, Pedersen T, Seidelin J og Weber T. Klinisk Risikostyring – en MTV-analyse af implementering på en dansk fødegang. ISBN: 87-988362-5-0. 2003. H:S, Hvidovre Hospital 54 Folkersen J. Kompendium i projektledelse. ISBN 87-988362-4-2. 2002. MTV-enheden, Hvidovre Hospital 55
Folkersen J. Litteratursøgning og evidensvurdering - en kort vejledning. ISBN 87-988362-3-4. 2002. MTV-enheden, Hvidovre Hospital 56 Vrangbæk C. og Folkersen J. Vejledning i organisatorisk analyse i MTV-projekter . 2002. Institut f Statskundskab KBH’s universitet og MTV-enheden, Hvidovre Hospital 57 Larsen RJ og Folkersen J. Vejledning i detailplanlægning af MTV-projekter. ISBN 87-988362-2-6. 2001. MTV-enheden, Hvidovre Hospital 58 Folkersen J. Værd at vide om MTV. ISBN 87-988362-1-8. 2001. MTV-enheden, Hvidovre Hospital 59 Folkersen J. Indholdsvejledning for problemformulering og projektbeskrivelse 2001. MTV-enheden, Hvidovre Hospital 60 Hylstrup,Lars. Ancher Sørensen,Henrik. Folkersen,Jørgen. Andreasen,Jacob. Bennich,Christian. Elektronisk patientjournal til osteoporoseambulatorium – en medicinsk teknologivurdering. København: Sundhedsstyrelsen, Medicinsk teknologivurdering, Puljeprojekter 2008; 8(1) HTA-lectures and abstracts in recent years, 2000-2006
J.Folkersen ” Use of non-evidence based information in Health Technology Assessment”. Foredrag i det internationale HTAi-møde Krakov, , juni 2004, Polen: Gehrchen, PM, Dahl,P. Kjær, T, Folkersen, J ”Medicinsk teknologivurdering af stabiliserende rygoperationer, præliminære resultater” Foredrag ved det danske MTV-årsmøde KBH, 2003 Holt-Petersen og Folkersen. ”To fill the gap between decision makers and HTA providers”. MTV- enhedens poster til Istahc konferencen i Canmore, Canada juni 2003 Folkersen, J Invited speaker:”Pragmatic science-based decisions”,Mar-2002 : Basel, DIA Euro Meeting 2002: "The Patient is waiting" Abstract on back surgery, Istahc-konferencen Berlin, juni 2002 Cronicle in ”Dagens medicin”: ”Vi må selv gå forrest”, 8 febr 2001 Chairman for workshop på Hvidovre Hospitals forskningsdag om ”evidensbaseret medicin” 19 nov 2001
Programme de formation-recherche « La philosophie des sciences en Autriche et en France au XXème siècle: histoires croisées, héritages, réceptions et influences réciproques » Compte rendu du workshop des 23 et 24 novembre 2007 Les premières journées organisées les 23 et 24 novembre 2007 – dans le cadre du programme de formation-recherche « La philosophie des sciences en Aut
THE η(1405), η(1475), f1(1420), AND f1(1510)Revised November 2013 by C. Amsler (Bern) and A. Masoni(INFN Cagliari). The first observation of the η(1440) was made in pp anni-hilation at rest into η(1440)π+π−, η(1440) → KKπ [1]. Thisstate was reported to decay through a0(980)π and K∗(892)Kwith roughly equal contributions. The η(1440) was also ob-served in radi