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LASA LABORATORY PVT. LIMITED
MATERIAL SAFETY DATA SHEET
SECTION 1. PRODUCT IDENTIFICATION
Product Name: Furosemide
Chemical Formula: C12H11CLN2O5S
Synonym: 4-Chloro-N-(2-furylmethyl)-5-
sulfamoylanthranilic acid
Company Identification: Lasa Laboratory Pvt Limited
Telephone No. - +91-251-2694321/2697340. SECTION 2. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name
Percent by Weight
SECTION 3. HAZARD IDENTIFICATION
Potential Acute Health Effects: Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant). CARCINOGENIC EFFECTS: Classified None. by NTP, None. by OSHA, None. by NIOSH. 3 (Not classifiable for human.) by IARC. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Classified Reproductive system/toxin/female, Reproductive system/toxin/male, Development toxin [POSSIBLE]. The substance is toxic to kidneys, liver, bladder, cardiovascular system. Repeated or prolonged exposure to the substance can produce target organs damage. Page 1 of 8
LASA LABORATORY PVT. LIMITED
SECTION 4. FIRST AID
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention. Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. SECTION 5. FIRE AND EXPLOSION
Flammability of the Product: May be combustible at high temperature. Auto-Ignition Temperature: Not available. Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.). Fire Hazards in Presence of Various Substances: Not available. Explosion Hazards in Presence of Various Substances: Page 2 of 8
LASA LABORATORY PVT. LIMITED

Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of
presence of static discharge: Not available. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use Special Remarks on Fire Hazards: Not available. Special Remarks on Explosion Hazards: Not available SECTION 6. ACCIDENTAL RELEASE MEASURES
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. SECTION 7. HANDLING AND STORAGE
Keep locked up Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. protective clothing If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes Keep away from incompatibles such as oxidizing agents, metals, acids. Keep container dry. Keep in a cool place. Ground all equipment containing material. Carcinogenic, teratogenic or mutagenic materials should be stored in a separate locked safety storage cabinet or room. Page 3 of 8
LASA LABORATORY PVT. LIMITED
SECTION 8. PERSONAL PROTECTION/EXPOSURE CONTROLS
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state and appearance: Solid. (Crystalline solid.) Page 4 of 8
LASA LABORATORY PVT. LIMITED

Ionicity (in Water): Not available.
Dispersion Properties: Dispersed in methanol. Very slightly dispersed in cold water, diethyl ether. See Solubility: Soluble in methanol, acetone. Very slightly soluble in cold water, diethyl ether. SECTION 10. REACTIVITY/STABILITY
Conditions of Instability: Not available. Incompatibility with various substances: Reactive with oxidizing agents, metals, acids. Special Remarks on Reactivity: Not available. Special Remarks on Corrosivity: Not available. SECTION 11. TOXICOLOGICAL INFORMATION
Routes of Entry: Eye contact. Inhalation. Ingestion. Toxicity to Animals: Acute oral toxicity (LD50): 800 mg/kg [Rabbit]. CARCINOGENIC EFFECTS: Classified None. by NTP, None. by OSHA, None. by NIOSH. 3 (Not by IARC. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive Development toxin [POSSIBLE]. The substance is toxic to kidneys, liver, bladder, cardiovascular system. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant), of ingestion, of inhalation Special Remarks on Toxicity to Animals: Not available. Special Remarks on Chronic Effects on Humans: Not available. Special Remarks on other Toxic Effects on Humans: Not available. Page 5 of 8
LASA LABORATORY PVT. LIMITED
SECTION 12. ECOLOGICAL INFORMATION
Possibly hazardous short term degradation products are not likely. However, long term degradation Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product Special Remarks on the Products of Biodegradation: Not available SECTION 13. DISPOSAL
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental SECTION 14. TRANSPORTATION
DOT Classification: Not a DOT controlled material (United States). Special Provisions for Transport: Not applicable. SECTION 15. REGULATORY INFORMATION
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: Furosemide California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: Furosemide TSCA 8(b) inventory: No products were found. Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Page 6 of 8
LASA LABORATORY PVT. LIMITED

WHMIS (Canada): Not controlled under WHMIS (Canada).
R36/37/38- Irritating to eyes, respiratory system and skin. R40- Possible risks of irreversible effects. R62- impaired fertility. R63- Possible risk of harm to the unborn child. National Fire Protection Association (U.S.A.): Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash SECTION 16 - ADDITIONAL INFORMATION
This document is intended only as a guide to the appropriate precautionary handling of material by a person tamed in chemical handling. The user is responsible for a determine the precautions & dangers of this chemical for his or her particular application depending on usage. Adequate protective clothing, including eye / face guards, approved respirators must be used to avoid contact with the material or breathing chemical vapors / fumes. Exposure to this product may cause adverse health effects. This chemical may interact with other substances. Since the potential uses are so varied, M/s. Lasa
Laboratory Pvt Limited. cannot warn of all of the potential dangers of use or interaction with chemicals
of materials. M/s. Lasa Laboratory Pvt Limited. warrants that, the chemical meets the specifications set
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LASA LABORATORY PVT. LIMITED
M/s. Lasa Laboratory Pvt Limited. Disclaims any other warranties expressed or implied with
regard to the product supplied hereunder its merchantability or its fitness for a particular purpose. The user should recognize that, this product can cause severe injury, especially if improperly handled or the known Page 8 of 8

Source: http://www.lasalabs.com/msds/MSDS_Furosemide.pdf