Le sildénafil présent dans Kamagra exerce une inhibition réversible de la PDE5, modulant la cascade GMPc et favorisant une vasodilatation localisée. L’absorption digestive varie selon la forme utilisée, comprimés classiques ou gels oraux. La distribution tissulaire est large et la liaison protéique élevée, avoisinant 96 %. La métabolisation hépatique génère un métabolite actif contribuant à l’effet pharmacologique global. La demi-vie reste courte, avec disparition plasmatique en quelques heures. Les interactions significatives concernent surtout les nitrés organiques et inhibiteurs puissants du CYP3A4. Dans les publications techniques, kamagra en ligne est souvent cité dans le cadre d’analyses comparatives portant sur les différences de formulations et de cinétique d’absorption.

Central nervous system depressants

CENTRAL NERVOUS SYSTEM DEPRESSANTS
Opioid Pain Relievers
Anxiolytics (also belong to psychiatric
medication category)
• codeine (in 222® Tablets, Tylenol® No. 1/2/3/4, Fiorinal® C,
Benzodiazepines
• heroin
• alprazolam (Xanax®)
• hydrocodone (Hycodan®, etc.)
• chlordiazepoxide (Librium®)
• hydromorphone (Dilaudid®)
• clonazepam (Rivotril®)
• methadone
• diazepam (Valium®)
• morphine (MS Contin®, M-Eslon®, Kadian®, Statex®, etc.)
• flurazepam (Dalmane®)
• oxycodone (in Oxycocet®, Percocet®, Percodan®, OxyContin®, etc.)
• lorazepam (Ativan®)
• pentazocine (Talwin®)
• nitrazepam (Mogadon®)
• oxazepam ( Serax®)
• temazepam (Restoril®)
Inhalants
Barbiturates
gases (e.g. nitrous oxide, “laughing gas”, chloroform, halothane,
• butalbital (in Fiorinal®)
• secobarbital (Seconal®)
volatile solvents (benzene, toluene, xylene, acetone, naptha and
hexane)
Buspirone (Buspar®)
nitrites (amyl nitrite, butyl nitrite and cyclohexyl nitrite – also known
as “poppers”)
Non-Benzodiazepine Hypnotics (also
belong to psychiatric medication category)
• chloral hydrate
• zopiclone (Imovane®)
• GHB (gamma-hydroxybutyrate)
• Rohypnol (flunitrazepam)
CENTRAL NERVOUS SYSTEM STIMULANTS
Amphetamines
Caffeine

• dextroamphetamine (Dexadrine®)
Methelynedioxyamphetamine (MDA)
• methamphetamine (“Crystal meth”)
• methylphenidate (Biphentin®, Concerta®, Ritalin®)
• mixed amphetamine salts (Adderall XR®)
3,4-Methelynedioxymethamphetamine (MDMA, Ecstasy)
(also has hallucinogenic actions)
Cocaine/Crack
Nicotine
Decongestants (alone or in combination with other
medications in allergy and cough and cold
products)
• phenylephrine
• pseudoephedrine (Sudafed®)
Herbal Stimulants (e.g. ephedra)
HALLUCINOGENS
Indolealkylamines
Cannabinoids
(especially “THC”/tetrahydrocannabinol, found in marijuana, hash,
• DMT (Dimethyltryptamine, from the bark of the Virola
• LSD (d-lysergic acid diethylamide, “Acid”)
• LSA (d-lysergic amide, from morning
Anticholinergics
• psilocybin (“Magic mushrooms”)
• deadly nightshade (Atropa belladonna)
• jimsonweed (Datura stramonium)
• scopolamine (Transderm-V®)
Phenylethylamines
Arylcycloalkylamines
• mescaline (found in peyote cactus)
• MDA (Methylenedioxyamphetamine)
• ketamine
• MDMA (Ecstasy, 3,4-methylenedioxymethamphetamine)
• PCP (Phencyclidine)
• PMA (Paramethoxyamphetamine)
• 2-CB (4-bromo-2,5-dimethoxyphenethylamine)
Salvinorin-A (from the plant Salvia divinorum)
• STP (2,5-dimethoxy-4-methylamphetamine)
• TMA (Trimethoxyamphetamine)
PSYCHIATRIC MEDICATIONS
Antipsychotics
Antidepressants
Typical (oral)
Tricyclic Antidepressants (TCAs)
• chlorpromazine (Largactil®)
• amitriptyline (Elavil®)
• flupenthixol (Fluanxol)
• clomipramine (Anafranil®)
• fluphenazine (Modecate®)
• desipramine (Norpramin®)
• haloperidol (Haldol®)
• doxepin
• loxapine
• imipramine (Tofranil®)
• methotrimeprazine (Nozinan®)
• nortriptyline (Aventyl®)
• perphenazine (Trilafon®)
• trimipramine (Surmontil®)
• pimozide (Orap®)
• trifluoperazine (Stelazine®)
Monoamine Oxidase Inhibitors (MAOIs)
• zuclopenthixol (Clopixol®)
• moclobemide (Manerix®)
• phenelzine (Nardil®)
Atypical (oral)
• tranylcypromine (Parnate®)
• aripiprazole (Abilify®)
Selective Serotonin Reuptake Inhibitors (SSRIs)
• clozapine (Clozaril®)
• olanzapine (Zyprexa®/Zyprexa® Zydis/Zyprexa®
• citalopram (Celexa®)
• escitalopram (Cipralex®)
• paliperidone extended release tablet (Invega®)
• fluoxetine (Prozac®)
• quetiapine (Seroquel®/Seroquel® XR)
• fluvoxamine (Luvox®)
• risperidone (Risperdal®/Risperdal® M-Tab/Risperdal®
• paroxetine (Paxil® and Paxil CR®)
sertraline (Zoloft®)
ziprasidone (Zeldox®)
Selective Serotonin and Norepinephrine Reuptake
Depot (long-acting) antipsychotic injections
Inhibitors (SNRIs)
• flupenthixol decanoate (Fluanxol® Depot)
• desvenlafaxine (Pristiq®)
• fluphenazine decanoate (Modecate® Depot)
• duloxetine (Cymbalta®)
• haloperidol decanoate (Haldol® Depot)
• venlafaxine (Effexor® XR)
• paliperidone palmitate long acting injection
Serotonin-2 Antagonists/Reuptake Inhibitor (SARI)
• pipotiazine palmitate (Piportil® Depot)
• risperidone (Risperdal® Consta)
trazodone (Desyrel®)
zuclopenthixol acetate (Clopixol® Accuphase)
• zuclopenthixol decanoate (Clopixol® Depot)
Norepinephrine and Dopamine Reuptake Inhibitors
(NDRIs)
Antiparkinsonian Agents
(for treatment of extrapyramidal side effects of
• bupropion SR (Wellbutrin® SR)
antipsychotics)
• bupropion XL (Wellbutrin® XL)
• benztropine (Cogentin®)
Noradrenergic/Specific Serotonergic Antidepressants
• biperiden
(NaSSAs)
• ethopropazine
• procyclidine (Kemadrin®)
mirtazapine (Remeron®)
trihexyphenidyl (Artane®)
• mirtazapine orally disintegrating tablet (Remeron
Non-Benzodiazepine Sedative/Hypnotics
(also belong to CNS depressants category)
Mood Stabilizers
• chloral hydrate
• carbamazepine (Tegretol®)
• zopiclone (Imovane®)
• lamotrigine (Lamictal®)
• lithium (Carbolith®)
Agents for Alcohol Dependence
• topiramate (Topamax®)
• valproic acid/divalproex (Epival®)
• acamprosate (Campral®)
• disulfiram (Antabuse®)
Adjunct in the treatment of mood disorders
• naltrexone (Revia®)
• L-tryptophan (Tryptan®)
Agents for Smoking Cessation
Anxiolytics
• nicotine (patch, gum, lozenge, inhaler)
(also belong to the CNS depressants category)
• varenicline (Champix®)
Benzodiazepines
• bupropion SR (Zyban®)
• alprazolam (Xanax®)
Opioid Substitution Therapy
• chlordiazepoxide (Librium®)
• clonazepam (Rivotril®)
• buprenorphine with naloxone (Suboxone®)
• diazepam (Valium®)
• methadone
• flurazepam (Dalmane®)
• lorazepam (Ativan®)
Opioid Antagonists
• nitrazepam (Mogadon®)
• oxazepam ( Serax®)
• naloxone (Narcan®)
• temazepam (Restoril®)
Barbiturates
• butalbital (in Fiorinal®)
• secobarbital (Seconal®)
Buspirone (Buspar®)

Source: http://knowledgex.camh.net/health_equity/interpreters/Documents/New_Drug_Chart_Glossary_November_2011.pdf