Ivf (in vitro fertilization) is the procedure where eggs are removed from a woman and the fertilization of the eggs by sperm i
IVF Costs (for those without Insurance Coverage) IVF (In Vitro Fertilization) Treatment Packages
To help with the financial burden of IVF, we have developed competitively priced packages.
The packages include in-cycle ultrasound monitoring & blood tests, IVF (egg retrieval, fertilization of the eggs by sperm,
& nurturing of the resultant embryos) & Embryo Transfer into the uterine cavity.
The packages do not include, if needed, pre-cycle blood tests, uterine evaluation, medications, pregnancy ultrasounds.
Other costs: Anesthesiologist fee is $400. If needed, ICSI (intracytoplasmic sperm injection) fee is $1,500. IVF (“Regular IVF” or “Mild or Minimal Stimulation IVF”) IVF Single Cycle Package: IVF Two Cycle Package:
If <35 y. o. at time of egg retrieval - $10,000. If 36-39 y. o. at time of egg retrieval - $11,000. If 40-44 y. o. at time of egg retrieval - $12,000. For details, restrictions, and questions, please call 949-387-3888. IVF Shared Risk Plan:
The IVF Shared Risk Plan is a Three-Cycle IVF Plan that offers a partial refund if a pregnancy beyond 12
gestational weeks is not achieved within three cycles over 12 months. Qualification criteria apply. Please contact us for details.
The amount refunded is based on age. <30 y. o. Alternative forms of IVF:
(In contrast to “Regular IVF” & “Mild or Minimal Stimulation IVF”)
“Natural IVF” or “Modified Natural IVF”
Single Cycle Package $5,000Three Cycle Package
For IVF Treatment Packages involving Egg Donors or Surrogates, please call or email us. Table 1: What are the different types of IVF? Comparison of the Different Ovarian Stimulation Prevention of LH Ovulation Trigger Luteal Phase Types of IVF: (“Regular IVF”) Alternative forms of IVF: “Natural IVF” “Modified Natural IVF” “Mild or Minimal Stimulation IVF”
Adapted from: Nargund G, et al. The ISMAAR proposal on terminology for ovarian stimulation for IVF. Hum Reprod. 2007;22:2801-4. Which type of IVF is right for me? (See also Table 1)
IVF: The first successful IVF baby was born in 1978. Since then it is estimated that 5 mil ion babies have been born
worldwide utilizing IVF. IVF has evolved over time, for example, the ways in which ovaries are stimulated to produce
fol icles (eggs). IVF was original y performed without ovarian stimulation, depending on the single dominant fol icle
ovulating women form each month to produce a single mature egg. Today this type of IVF would be cal ed “Natural” or
“Modified Natural” IVF. IVF then evolved into using Clomiphene or Clomiphene & FSH/HMG injections to stimulate the
ovaries to form more than one dominant fol icle (egg). Today this type of IVF would be cal ed “Mild or Minimal Stimulation
IVF.” Final y IVF evolved to having ovarian stimulation occur with a daily FSH/HMG injection for about ten days. This
most successful method of ovarian stimulation has been dominant for the past 20+ years & thus is what is simply cal ed
“IVF” (or “Regular IVF”) – it is the type of IVF successful y used in the majority (>99%) of the world’s 5 mil ion IVF
babies. The Alternative forms of IVF (“Natural,” “Modified Natural,” “Mild or Minimal Stimulation”) are thus a revisiting of
the past, differing in how the ovaries are stimulated to produce mature fol icle(s) [egg(s)]. When discussing these types of
IVF, aside from ovarian stimulation methods, everything else is the same, such as the procedures in the lab (how the
eggs are fertilized, developed as embryos, etc.).
For the vast majority of women, “Regular IVF” is the method with the highest chance of success.
For example, a 2013 study estimated for a “Natural IVF” cycle “the pregnancy and live birth rates per initiated cycle were
19.2% and 15.2%, respectively, in patients <35 years old” [1]; the comparable “Regular IVF” rates were much higher, 47.6% and 41.5%, respectively, (2010 USA rates). Why is this? The emphasis with IVF should always be egg/embryo quality over quantity, but usually reasonablequantity will increase the chance of quality. With “Natural IVF,” only 1
fol icle (egg) typical y forms, & with “Minimal” IVF the goal is 2 to 7 fol icles (eggs); in contrast, with “Regular IVF” the goal
is to develop a larger group of 10 to 15 fol icles (eggs) if possible. Because of the larger cohort, the chance of obtaining &
fertilizing egg(s), which become excel ent embryo(s) for transfer into the uterus is greater, and thus, so is the pregnancy
rate. Furthermore, with “Regular IVF,” in addition to the embryo(s) transferred in the cycle, there is a good chance of
having additional embryos to freeze for later use. This is not the case with “Natural IVF” with only one embryo to transfer,
there are none to freeze. Frozen-thawed embryos commonly result in conception, so if one includes pregnancies
resulting from frozen-thawed embryos, the advantage of “Regular IVF” over “Natural IVF” for live birth rate per initiated
More Details: “Natural IVF” is defined as a cycle “in which the woman does not receive drugs to stimulate her ovaries to produce more follicles.
Instead, follicles develop naturally” [1]. The actual per embryo implantation (pregnancy) rate with unstimulated “Natural IVF”
“compares favorably” with “Regular IVF.” The problem is that because there is only often one follicle forming, only 71% of cycles
started proceed to retrieval, furthermore, the percentage of cycles that proceed to ET (embryo transfer) are 54% for the youngest
patients to 23% for patients >42 years old [1]. So many cycles that are started with “Natural IVF” never proceed to retrieval or
Additionally, with “Minimal Stimulation IVF,” typically Clomiphene is one of the medications used to stimulate the ovaries.
Because of Clomiphene’s potentially negative effects on the uterine lining, all embryos formed in these cycles are often frozen to be
transferred later. Thus often multiple cycles are performed with all the embryos developed frozen; the accumulated frozen embryos
are then thawed & later used in an embryo transfer.
Alternative forms of IVF such as “Natural” & “Minimal” IVF may be a desired option if one needs IVF and
Does not want to take any ovarian stimulation meds or wants to use clomiphene &/or less meds and is wil ing to
accept the lower pregnancy rates per cycle initiated, or is wil ing to undergo multiple cycles, without fresh embryo
transfer, in order to accumulate frozen embryos for later thaw & transfer, or
Is a “poor responder” and cannot recruit and form multiple dominant fol icles under “Regular IVF” stimulation.
Alternative forms of IVF should not simply be chosen because, e.g. it seems* less expensive than “Regular IVF” (*often it
turns out not to be). Alternative forms of IVF should be chosen if one needs IVF & the above applies.
In Summary: Per cycle initiated, alternative forms of IVF have far less chance of resulting in embryo(s) for transfer into the uterus and thus pregnancy. The embryos that do form with Alternative forms of IVF have similar implantation rates (pregnancy rates) as “Regular IVF” embryos. The consequences of these two facts are pregnancy rates with Alternative forms of IVF are less than with “Regular IVF.” If one needs IVF (IVF is especially effective at treating tube &/or sperm problems) it is best to choose the type of IVF that maximizes the chance of a successful conception, for most women, this is “Regular IVF.” ------------------------------------------------------------------------------------------------------------------------------------------------------------------
[1] Gordon JD, et al. Utilization and success rates of unstimulated in vitro fertilization in the United Sates. Fertil Steril 2013;100:392-5.
Effects of Food and Drug Administration-approved medications forAlzheimer’s disease on clinical progressionMichelle M. MielkeJeannie-Marie Leoutsakos, Chris D. Corcoran, Robert C. GreenMaria C. Norton,Kathleen A. W, JoAnn T. Tschanz,, Constantine G. LaDepartment of Psychiatry, Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD,