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S K I N & A L L E R G Y N E W S • A p r i l 2 0 0 7 Imiquimod Useful Before, After Cancer SurgeryPretreatment can shrink a BCC lesion, and use after matol. Surg. 2005;31:1399-403). A total of 20 patients who each had two nevi excised surgery may improve scarring and prevent recurrence. were instructed to apply topical im- in the SCC study, he reported at the meet- iquimod to one and a control substance to ing. Publication of the studies is pending, B Y D A M I A N M C N A M A R A
look at . ways to treat skin cancers oth- the other. “The cosmetic outcome was rat- to support publication. Dr. Tillman is on scale included a pink appearance as a bad “I use Aldara primarily out of necessi- ty,” said Dr. Tillman. His practice covers skin cancer. Adjunctive topical imiquimod Oncologists
asked if imiquimod’s clinical effect is age treatments but
dependent. “The answer in my practice is ‘dermatologists
no. A 105-year-old patient got a nice result, tend to do one
ministration in July 2004. Multiple studies thing at a time.’
following curettage without electrodesic- cation for basal cell carcinoma. Dr. Rigel “but interestingly enough, we as derma- with either nodular or superficial BCC le- tologists tend to do one thing at a time,” shrink a BCC lesion, which should yield a sions. One week after curettage, patients smaller and more effective surgery, said Dr.
of Medicine, New York. “Surgery and ra- group. “So Aldara delays healing, but by “Six weeks seems to work well,” Dr.
diation therapy are well described as ef- 2 months, everyone healed,” he said. The improves scarring, perhaps by releasing in- terferon. In one study of 15 patients who At 1 year, there were zero recurrences.
significantly impact our practices in the side treated with imiquimod better in ap- There were excellent cosmetic results, su- next 5-10 years,” predicted Dr. Darrell S.
pearance at 6 months (Plast. Reconstr.
BCC or 86 patients with squamous cell car- perior to electrodesiccation and curettage, Rigel, clinical professor of dermatology at cinoma (SCC), said Dr. Donald K. Tillman, a dermatologist practicing in Hays, Kan.
Military Experts Say Newer Hemostatic Dressings Beat Gauze B Y J O H N R . B E L L
O riginal article Scand J Work Environ Health 2006;32(5):339–348 Do burned-out and work-engaged employees differ in the functioning of thehypothalamic-pituitary-adrenal axis?by Saar Langelaan, MSc,1, 2 Arnold B Bakker, PhD,2, 3 Wilmar B Schaufeli, PhD,1, 2 Willem van Rhenen,MSc,4 Lorenz JP van Doornen, PhD 2, 5Langelaan S, Bakker AB, Schaufeli WS, van Rhenen W, van Doornen LJP. Do burned-out