Recalls, Market Withdrawals, & Safety Alerts > HOSPIRA ISSUES A VOLUNTARY N. Page 1 of 2
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HOSPIRA ISSUES A VOLUNTARY NATIONWIDE RECALL OF ONE LOT OF METOCLOPRAMIDE INJECTION, USP, AND TWO LOTS OF ONDANSETRON INJECTION, USP, DUE TO GLASS (GLASS STRANDS) PARTICULATES CAUSED BY GLASS SUPPLIER DEFECT Contact:
1-224-212-2357 FOR IMMEDIATE RELEASE - October 1, 2013 - Hospira, Inc. (NYSE: HSP), announced today it initiated a
voluntary nationwide recall of one lot of Metoclopramide Injection, USP, 10 mg/2 mL (5 mg/mL), NDC 0409-
3414-01, Lot 28-104-DK and two lots of Ondansetron Injection, USP, 4 mg/2 mL, (2 mg/mL), NDC 0409-4755-
03, Lots 29-484-DK and 29-510-DK. This action is due to a confirmed vial defect where glass particulate matter
(glass strands) were identified as being affixed to the inside of the vial walls. There is potential for the glass
particulates to dislodge into the solution. The administration of an injectable with the presence of foreign particulates may potentially result in local
inflammation, thrombophlebitis, and/or low-level allergic response. Signs and symptoms could include redness,
pain, swelling at the site, fever, shortness of breath, tachycardia, nausea and vomiting. Additionally, the
particulate contaminants could potentially act as an emboli and impede blood flow causing tissue/organ damage,
especially in vulnerable patients such as those undergoing surgery, immunosuppressed individuals, infants,
children and the elderly, as well as patients with micro or macrovascular disease, such as cardiac and renal
disease, who may be more at risk since their vasculature, and end organs, are already compromised. To date, Hospira has not received reports of any adverse events associated with this issue for these lots. This
recall is being conducted as a precautionary measure. Hospira advised customers of this recall in a letter dated
September 24, 2013. Hospira has completed an investigation where the root cause findings are attributed to a
supplier’s manufacturing glass defect. As a result of this issue, Hospira is working with its supplier on
implementing corrective and preventive actions. Metoclopramide Injection, USP, 10 mg/2 mL (5 mg/mL), NDC 0409-3414-01, Lot 28-104-DK (the lot number
may be followed by a 01), is packaged in a 2 mL single-dose fliptop vial, with an expiration date of October 1,
2014. Ondansetron Injection, USP, 4 mg/2 mL (2 mg/mL), NDC 0409-4755-03, Lots 29-484-DK and 29-510-DK (the
lot numbers may be followed by a 01) are packaged in a 2 mL single-dose fliptop vial, with an expiration date of
May 1, 2015. Both products are packaged as 25 units per carton/100 units per case in glass fliptop vials. The affected lots were distributed nationwide between June 2013 and September 2013 to
wholesalers/distributors, hospitals and pharmacies. Anyone with an existing inventory should stop use and distribution, quarantine the product immediately, and call
Stericycle at 1-877-497-3125 between the hours of 8am to 5pm ET, Monday through Friday, to arrange for the
return of the product. Replacement product from other lots is available. For clinical inquiries, please contact Hospira using the information provided below. Hospira Contact Contact Information Areas of Support Hospira Global Complaint Management
http://www.fda.gov/Safety/Recalls/ucm370658.htm?source=govdelivery&utm_medium=. 10/17/2013
Recalls, Market Withdrawals, & Safety Alerts > HOSPIRA ISSUES A VOLUNTARY N. Page 2 of 2
Hospira Medical Communications
Any adverse reactions or quality problems experienced with the use of this product may be reported to the U.S.
Food and Drug Administration's (FDA) MedWatch Adverse Events Program either online, by regular mail or by
z Online: www.fda.gov/medwatch/report.htm1
z Regular mail: use postage-paid, pre-addressed Form FDA3500 available at
z Fax: 1-800-FDA-0178
This recall is being conducted with the knowledge of the U.S. Food and Drug Administration. About Hospira Hospira, Inc. is the world's leading provider of injectable drugs and infusion technologies. Through its broad,
integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver
safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees. Learn more at www.hospira.com3 4.
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Patient information leaflet Please read this information leaflet carefully before you take or use the medicine. This medicine has been prescribed for your personal use and you must not pass it on to anyone else. The medicine could be harmful to them even if they have the same symptoms as you. Keep this information leaflet - you may wish to read it again later. Doxycycline Axapharm® What i