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Grape Seed Extract Important
Recommendation in Type 2
Cranberry Effective in Chronic
Cranberry juice and cranberry extracts have shown Increased oxidative stress is a major factor in the risk of the benefit in preventing and treating urinary tract infections chronic complications of diabetes. Individuals with diabetes in several double-blind studies. New data indicates that it typically have elevated levels of free radicals and oxidative may also be of benefit in men with non-bacterial chronic compounds. These highly reactive compounds bind to and destroy cellular compounds. They also greatly increase the inflammatory process by adding fuel to their destructive fire Prostatitis is a condition that occurs when the prostate via increased formation of inflammatory mediators like C- becomes inflamed or swollen. It is considered a chronic condition when the symptoms last for several weeks. One of the critical goals in diabetes prevention and treatment Chronic non-bacterial prostatitis most often is the result is to flood the body with a high level of antioxidant of damage or inflammation to the connective tissue compounds to counteract the negative effects of free radicals barrier of the inner lining of prostate that prevents and pro-oxidants. Two critical antioxidants for diabetics are potentially harmful materials in urine from breaking alpha-lipoic acid and flavonoid-rich extracts. through to deeper tissues. Symptoms consist of: • voiding issues including weak or intermittent The beneficial effects of proanthocyanidin-rich extracts like urinary stream, straining, hesitancy, terminal grape seed and pine bark (Pycnogenol) extract in battling the complications of diabetes are numerous. Proanthocyanidin • storage issues including urgency, frequency, • Are more potent and effective against a broader range of oxidants than the traditional antioxidant nutrients Forty-two men with chronic non-bacterial prostatitis vitamins C and E, beta-carotene, selenium, and zinc. received either 1500 mg of the dried powdered • Increase intracellular vitamin C levels and preserve cranberries per day for 6 months or no cranberry important antioxidants like gluthathione (GSH). treatment. At the end of the study, the cranberry group • Protect against damage to arteries and other blood experienced significant improvements in International Prostate Symptom Score (IPSS), quality of life, and urine • Decrease the leakiness and breakage of small blood flow and other voiding parameters, but the control group vessels, preventing easy bruising, and promoting did not. The mean IPSS declined by 4.48 points in the cranberry group compared with an increase of 1.43 in the One of the major complications of diabetes is an increased risk for heart attacks and stroke. In a very detailed 4-week Vidlar A, Vostalova J, Ulrichova J, et al. The double-blind study, grape seed extract (600 mg/day) was effectiveness of dried cranberries (Vaccinium compared to a placebo in 32 patients with type 2 diabetes. macrocarpon) in men with lower urinary tract symptoms. Results showed impressive reductions in markers for Br J Nutr. 2010 Oct;104(8):1181-9. Epub 2010 Aug 31. inflammation and oxidative stress. For example, whole blood glutathione levels were 3595 mmol/l in the GSE group compared to 2359 mmol/l in the placebo. The level of C- Summer Special !!!
reactive protein was 2.2 mg/l in the GSE group and 3.2 mg/l in the placebo group. To achieve these reductions within one 15% off total grocery purchase
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BioSil's ch-OSA®: The Scientific
Breakthrough in Collagen
Your Bones In a clinical trial women were divided into two
Collagen has been called the most important building block in the groups: BioSil® and Placebo. The BioSil® group took ch- human body. It comprises over a third of your body's proteins. It OSA®, 1000 mg/day of calcium, and 800 IU/day vitamin D. makes up 75% of your skin. It is a major supporting structure for The Placebo group took only the calcium and vitamin D. Bone your bones, joints, and vital organs. That's why collagen is collagen synthesis was increased in the BioSil® group essential for beautiful skin, hair, and nails as well as healthy compared to placebo. Placebo subjects lost 1.22% in bone bones and joints. But starting at age 21, collagen begins to mineral density (BMD) at the hip region whereas the BioSil® diminish. By age 30, the signs are visible. For years, scientists subjects (6 drops ch-OSA®/day) gained 0.78 %. That's a searched for a method that would give the human body the ability difference of 2.00%, or 200% higher than the threshold of to regenerate its own collagen. But it wasn't until BioSil®'s clinical relevance. Published Clinical Trial Results: Spector et al landmark discovery of ch-OSA® that genuine collagen generation, through oral delivery, became a reality. Today, rigorous double-blind, placebo-controlled clinical trials prove that BioSil®'s patented ch-OSA® reduces fine lines and wrinkles, Research Update on SAMe (S-
increases skin elasticity, strengthens and thickens hair, hardens Adenosylmethionine)
nails, and promotes healthy bones and joints. BioSil®'s historic discovery is now considered the scientific breakthrough in collagen. Clinically Tested - Safe and Effective You'll be
S-Adenosylmethionine (SAMe) is an important physiologic happy to know that BioSil's ch-OSA® collagen generator has agent that is involved in more than 40 biochemical reactions been the subject of the most rigorous testing procedure known: in the body. It functions closely with folic acid and vitamin the double blind, placebo-controlled university conducted clinical B12 in “methylation” reactions. Methylation is the process of trial. It is considered the gold standard in measuring results, and adding a single carbon unit (a methyl group) to another is employed by the pharmaceutical companies. The clinical molecule. SAMe is many times more effective in transferring results, now published in peer-reviewed medical journals, were as methyl groups than other methyl donors. Methylation dramatic as they were statistically significant. Subjects taking reactions are critical in the manufacture of many body BioSil's ch-OSA® showed a marked decrease in fine lines and components, especially brain chemicals, as well as in wrinkles, greater skin elasticity, thicker and stronger hair, harder detoxification reactions. Not surprisingly, the principal uses nails and an increase in bone mineral density (BMD) at the of SAMe are in supporting brain and liver health as well as critical hip region. Best of all, BioSil's ch-OSA® has been proven safe. The condition of your hair, skin, and nails depends on
Benefits for Healthy Joints:
three proteins: Collagen 'plumps' your skin, removing fine lines
SAMe has also demonstrated impressive results in improving and wrinkles, and preventing them from forming. In addition, joint health in double-blind studies. A deficiency of SAMe in collagen is essential for strong, healthy bones and joints. the joint tissue, just like a deficiency of glucosamine, leads to Keratin is the protein that's packed into your hair shaft. It gives
loss of the gel-like nature and shock-absorbing qualities of your hair thickness, body, strength, and elasticity. Plus, keratin cartilage. As a result, cartilage can degenerate leading to pain Elastin gives your skin its ability to stretch and 'bounce back'
In double-blind trials, SAMe has demonstrated similar (elasticity) preventing fine lines and wrinkles. With age collagen, reductions in pain scores and clinical symptoms to those keratin and elastin decline. BioSil® Hair Skin Nails with produced by nonsteroidal anti-inflammatory drugs (NSAIDs) clinically proven ch-OSA®, is specifically formulated to help like ibuprofen, indomethacin, naproxen, nabumetone, nourish your body's 3 beauty proteins and restore them to more celecoxib, and piroxicam. Unlike the drugs which are youthful levels. Your Skin By generating collagen in your skin,
exerting pharmacological effects, SAMe appears to produce BioSil® Hair Skin Nails decreases fine lines and wrinkles, and its benefits simply by delivering nutritional support to increases skin elasticity. Users also report it adds a radiant quality cartilage cells thereby helping them to function more to their skin. Published Clinical Trial Results: Barel et al 2005 Your Hair BioSil® Hair Skin Nails helps your hair grow
thicker and stronger. The ch-OSA® in BioSil® has been Two new studies compared SAMe (1200 mg/d) to the drugs clinically shown to significantly increase the diameter of each nabumetone (Relafene, 1000 mg/d) and celecoxib (Celebrex, hair shaft - adding fullness and body to your hair. In addition, 200 mg/d) in patients showing signs and symptoms of BioSil® Hair Skin Nails helps make your hair stronger, more cartilage degeneration of the knees. In the first study, SAMe elastic, and more break resistant. Published Clinical Trial Results: was shown to be equal to nabumetone in effectively reducing pain intensity from baseline as well as in patient and Your Nails BioSil® has been clinically shown to strengthen your
physician assessment; and index scores of joint function. In nails, making them more break resistant. The BioSil® nail the study comparing SAMe to Celebrex, SAMe showed a phenomenon has given birth to a new expression: 'Unbreakable slower onset of action but was judged as effective as Beauty.' Published Clinical Trial Results: Barel et al 2005 celecoxib, but without the side effects. 200% higher than the threshold of clinical relevance. Published Given the known risks for significant side effects with use of Clinical Trial Results: Spector et al 2008 NSAIDs, the results from these new studies provide additional evidence that a natural approach that focuses on delivering improved nutrition to joint tissues is a more rationale approach.
EDITORIAL 107 Medicações sistêmicas e queixa ocular: Alguma correlação? A o ser convidado para escrever este editorial, pensei em um tema diferen- te, que pudesse oferecer alguma contribuição ao leitor. Refiro-me aospossíveis efeitos colaterais oculares associados com medicaçõessistêmicas, comumente utilizadas por nossos pacientes. Estaria cada oftalmologis-ta ciente que dr