Correspondence The ﬁ rst case of H7N9 high H7N9 viral loads (4·5–51·4 × 107 side-eﬀ ects of statins. Sinzinger and copies per mL) were found in the O’Grady1 reported statin intolerance inﬂ uenza in Taiwan two sputum specimens and one in elite soccer players,2 and the Published Online We report here the ﬁ rst case of H7N9 throat-swab specimen (collected on PRIMO study3
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Clinicalgeriatrics.comT I P S H E E T
Expert information from Healthcare Professionals Who Specialize in the Care of Older Adults
Ten Medications Older Adults Should Avoid
or Use with Caution
Because older adults often experience chronic health conditions that
require treatment with multiple medications, there is a greater likelihood of experiencing unwanted drug side effects. Older people can also be more sensitive to certain medications. To help you make better informed or pharmacist. Do not stop taking any medication decisions about your medications, and to lower your chances of overmedi- without first talking to cation and serious drug reactions, the American Geriatrics Society Foun- dation for Health in Aging recommends that older people be cautious about using the following types of medications, including some that can be purchased without a prescription (over-the-counter). n Medication
USE WITH CAUTION
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
n AVOID long-acting NSAIDs like indomethacin (Indocin) and piroxicam (Feldene).
n Shorter-acting NSAIDs like ibuprofen (Advil, Motrin) and salsalate (Disalcid) are n If you take NSAIDs regularly, and have a history of ulcers or are 75 years of age or older, you may need to protect your stomach against bleeding with a prescription medication such as misoprostol (Cytotec) or a proton pump inhibitor such as omeprazole (Prilosec).
n Because of the increased risk of bleeding, don’t use NSAIDs together with aspirin, clopidogrel (Plavix), dabigatran (Pradaxa), dipyridamole (Persantine), prasugrel (Effient), ticlopidine (Ticlid), or warfarin (Coumadin).
AVOID digoxin (Lanoxin) in doses greater than 0.125 mg.
n Digoxin is used to treat heart failure and irregular heartbeats. Medication
AVOID Certain Diabetes Drugs
These can cause severe low blood sugar.
n Glyburide (Diabeta, Micronase) and chlorpropamide (Diabinese) AVOID Muscle Relaxants
n Such as cyclobenzaprine (Flexeril), methocarbamol (Robaxin), and carisoprodol (Soma), and similar medications.
problems urinating. Plus, there is little AVOID Certain Medications used for Anxiety
They can increase your risk of falls, as and/or Insomnia
well as cause confusion. Because it takes your body a long time to get rid of these n Benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), or chlordiazepoxide (Librium) n Sleeping pills such as zaleplon (Sonata) and zolpidem (Ambien) AVOID Certain Anticholinergic Drugs
n Antidepressants amitriptyline (Elavil) and imipramine (Tofranil) n Anti-Parkinson drug trihexyphenidyl (Artane) n Irritable bowel syndrome drug dicyclomine (Bentyl) n Overactive bladder drug oxybutynin (Ditropan) AVOID the Pain Reliever meperidine (Demerol)
It can increase the risk of seizures and AVOID Certain Over-the-Counter Products
n AVOID products that contain the antihistamines diphenhydramine without a prescription, they are not risk (Benadryl) and chlorpheniramine (AllerChlor, Chlor-Trimeton) (particularly in men with an enlarged prostate). vision, constipation, problems urinating, n AVOID over-the-counter sleep products, like Tylenol PM, which If you are NOT being treated for psychosis, AVOID using
and other side effects, as well as increase n Such as haloperidol (Haldol), risperidone (Risperdal), or quetiapine AVOID Estrogen pills and patches
n Typically prescribed for hot flashes and other menopause-related FHA FOUNDATION FOR HEALTH IN AGING www.healthinaging.org
NEW MICROBIOLOGICA, 30 , 346-349, 2007 Pharmacokinetics and pharmacodynamics in HAART and antibiotic therapy Marta Boffito St. Stephen’s Centre, Chelsea and Westminster Hospital, London, UK Therapeutic agents used to inhibit the HIV replication are used in combination. The achievement of effective plas-ma concentrations of the drug in its active form, and sustaining such concentrati