Microsoft word - appendix 10 carcinogens

Appendix 10: Carcinogens
The list below is a compilation of substances classified as carcinogens by either the International Agency for Research on Cancer (IARC) and the National Toxicology Program (NTP). Some of these substances are classified as “Select Carcinogens” and require special work practices. See Appendix 1 for the definition of “Select Carcinogen” Chemical Name
AF-2 (2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide) 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole Analgesic mixtures containing phenacetin Chemical Name
N,N-Bis(2-chloroethyl)-2-naphthylamine (chlornaphazine) Bis(chloromethyl)ether (technical grade) 1,4-Butanediol dimethanesulfonate (Busulphan Myleran) Chlorinated paraffins (C12 60% Chlorine) 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea Chloromethyl methyl ether (technical-grade) p-Choro-o-toluidine and its strong acid salts Chemical Name
Dantron (Chrysazin; 1, 8-Dihydroxyanthraquinone) 3,3'-Dichloro-4-4'-diaminodiphenyl ether Chemical Name
Trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2- Estrogens (not conjugated) estradiol-17ß Estrogens (not conjugated) ethinylestradiol Etoposide in combination with cisplatin and bleomycin 2-(2-Formylhydrazino)-4-(5-(5-nitro-2-furyl)thiazole Glu-P-1 (2-amino-6-methyldipyrido[1, 2-a:3', 2'-d]imidazole) Glu-P-2 (2-aminodipyrido[1, 2-a:3',2'-d]imidazole) Chemical Name
Inorganic-acid mists, containing sulfuric acid IQ (2-Amino-3-methylimidazo[4,5-f]quinoline) MeA-a-C (2-Amino-3-methyl-9H-pyrido[2, 3]indole) MelQ (2-Amino-3, 4-dimethylimidazol[4, 5f]quinoline MelQx (2-AMino-3, 8-dimethylimidazo[4, 5-f]quinoxaline 8-Methoxysoralen (methoxsalen) plus ultraviolet A radiation 4,4'-Methylene bis(2-chloroaniline) (MBOCA) 4,4'-Methylene bis(N,N-dimethylbenzenamine) 2-Methyl-1-nitroanthraquinone (uncertain purity) N-Methyl-N'-nitro-N-nitrosoguanidine (MNNG) Michler's ketone [4,4’-(Dimethylamino)benzophenone] Mineral oils, untreated and mildly-treated MOPP and other combined chemotherapy including 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2- Chemical Name
1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone N-[4-(5-Nitro-2-furyl)-2-thiaxolyl]acetamide 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-butanone (NNK) Oestrogen-progestogen therapy, post menopausal Palygorskite (long fibers, > 5 micrometers) Panfuran S (containing dihydorxymethylfuratrizine) Chemical Name
Phlp (2-Amino-1-methyl-6-phenyl-imidazo[4,5-b]pyridine) Silica, crystalline cristobalite (respirable size) Silica, crystalline tridymite (respirable size) Silica, crystalline quartz (respirable size) Strong inorganic acid mists containing sulfuric acid 2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD) Chemical Name
Trichlormethine (trimustine hydrochloride) Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b] indole) Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole) (a) International Agency for Research on Cancer (IARC): 1. Carcinogenic to humans with sufficient epidemiological evidence 2A. Probably carcinogenic to humans with (usually) at least limited human evidence 2B. Probably carcinogenic to humans, but having (usually) no human evidence For a complete listing of IARC carcinogens, mixtures and exposure circumstances, see http://www.iarc.fr a. Known to be carcinogenic with evidence from human studies b. Reasonably anticipated to be a carcinogen, with limited evidence in humans or sufficient evidence in experimental animals More information on NTP carcinogens can be found at: http://ntp-server.niehs.nih.gov

Source: http://www.chemicalsafety.eku.edu/sites/chemicalsafety.eku.edu/files/carcinogens_0.pdf

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