Le sildénafil présent dans Kamagra exerce une inhibition réversible de la PDE5, modulant la cascade GMPc et favorisant une vasodilatation localisée. L’absorption digestive varie selon la forme utilisée, comprimés classiques ou gels oraux. La distribution tissulaire est large et la liaison protéique élevée, avoisinant 96 %. La métabolisation hépatique génère un métabolite actif contribuant à l’effet pharmacologique global. La demi-vie reste courte, avec disparition plasmatique en quelques heures. Les interactions significatives concernent surtout les nitrés organiques et inhibiteurs puissants du CYP3A4. Dans les publications techniques, kamagra en ligne est souvent cité dans le cadre d’analyses comparatives portant sur les différences de formulations et de cinétique d’absorption.

List by therapeutic class

REGENCY PREFFERED FORMULARY EFFECTIVE 1/01/04
FORMULARY NEW ADD LIST
Aromasin
Beconase AQ
Benicar
Copegus
Dovonex
Femara
Lantus
Nimotop
Pegasys
Rebif
Singular Granules
Soriatane
Vfend
PRODUCTS NO LONGER ON FORMULARY
Non-formulary
Formulary
Generic nifedipine, diltiazem, verapamil Generic nifedipine, diltiazem, verapamil List by Therapeutic Class
PAR=Prior Authorization QL=Quantity Limits
ST=Step Therapy required
VA=Value Added List
ANTI-INFECTIVES
MENTAL HEALTH
amitriptyline/chlordiazepoxide (Limbitrol®) amphetamine/dextroamphetamine (Adderall®) chloroquine phosphate (Aralen phosphate®) erythromycin ethyl succinate (EryPed®, EES®) erythromycin/sulfisoxazole (Pediazole®) trimethoprim/sulfamethoxazole (Septra®, Stromectol® Vancocin® Zithromax® (QL) ANTIVIRALS
NEUROLOGICAL
chloral hydrate (Somnote®, Aquachloral®) BONE AND JOINT
Cuprimine® Enbrel® (PAR) Kineret® (PAR) OPHTHALMIC
acetazolamide (Diamox®) (VA)
ONCOLOGY
phenylephrine ophthalmic (AK-Dilate®) pilocarpine ophthalmic (Isopto Carpine®) polymyxin B/trimethoprim ophthalmic (Polytrim®) prednisolone acetate ophthalmic (Pred Forte®) CARDIOVASCULAR
prednisolone sodium phosphate ophthalmic sodium sulfacetamide ophthalmic (Bleph-10®) hydrochlorothiazide/triamterene (Dyazide®) (VA) lisinopril (Zestril, Prinivil®) lisinopril/hctz (Zestoretic, Prinzide®) methyclothiazide (Enduron®) methyldopa/hctz (Aldoril®) metoprolol (Lopressor®) (VA) PAIN/INFLAMMATION/HEADACHE
nitroglycerin (Nitrobid, Nitrostat®) (VA) acetominophen/butalbital/caffeine (Fioricet®) acetominophen/butalbital/caffeine/codeine aspirin/butalbital/caffeine (Fiorinal®) aspirin/butalbital/caffeine/codeine (Fiorinal aspirin/caffeine/orphenadrine (Norgesic®) quinidine sulfate (Quinidex Extentabs®) (VA) aspirin/carisoprodol/codeine (Soma Compound ergot/caff/bell alk/phenobarb (Cafergot P-B®) sulindac (Clinoril®) tramadol (Ultram®) Cafergot® DIABETES
glipizide (Glucotrol, Glucotrol XL®) (VA) Humalog insulins® Humulin insulins® Iletin II insulins® RESPIRATORY
aminophylline (Panamin®) cromolyn inhaled (Intal®) dyphylline (Dilor®) EAR/NOSE/THROAT
benzocaine/antipyrine otic (Auralagan®) guaifenesin/hydrocodone (Vicodin Tuss®) SKIN
amcinonide (Cyclocort®)
ENDOCRINE/HORMONES
bacitracin/HC/neomycin/polymyxin B ophthalmic betamethasone valerate topical (Luxiq®) betamethasone/clotriamazole (Lotrisone®) levothyroxine (Levothroid®, Levoxyl®) (VA) hydrocortisone/pramoxine topical (Proctocream ketoconazole topical (Nizoral topical®) nystatin/triamcinolone topical (Mycolog-II®) silver sulfadiazine topical (Sivadene®) timolol ophthalmic (Betimol, Timoptic®) GASTROINTESTINAL
loperamide (Imodium®) metoclopramide (Reglan®) (VA) nizatidine (Axid®) polyethylene glycol/electrolytes (Colyte®) trimethobenzamide (Tigan®) ursodiol (Urso®) Actigall® WOMEN'S HEALTH
estradiol transdermal (Estraderm®, Alora®, Ortho Micronor® Ortho Tri-Cyclen® Ortho-Cept® IMMUNE SYSTEMS
LIPID LOWERING
lovastatin (Mevacor®) Advicor® Colestid® Lipitor® Niaspan® Alphabetized List
PAR=Prior Authorization QL=Quantity Limits apply
VA=Value Added List
ST=Step Therapy
required
acetaminophen/hydrocodone (Vicodin, Lortab®) ketoconazole topical (Nizoral topical®) acetominophen/butalbital/caffeine (Fioricet®) acetominophen/butalbital/caffeine/codeine (Fioricet with Codeine®) acetominophen/dichloralphenazone/ isometheptene (Midrin®) levothyroxine (Levothroid®, Levoxyl®) (VA) lisinopril/hctz (Zestoretic, Prinzide®) amitriptyline/chlordiazepoxide (Limbitrol®) amoxicillin/clavulanate (Augmentin®) amphetamine/dextroamphetamine (Adderall®) ampicillin (Omnipen®) anthralin topical (Drithocreme®) Anzamet® (QL) aspirin/butalbital/caffeine (Fiorinal®) aspirin/butalbital/caffeine/codeine (Fiorinal aspirin/caffeine/orphenadrine (Norgesic®) aspirin/carisoprodol/codeine (Soma Compound Metrogel® metronidazole (Flagyl®) mexiletine (Mexitil®) benzocaine/antipyrine otic (Auralagan®) betamethasone valerate topical (Luxiq®) betamethasone/clotriamazole (Lotrisone®) bethanechol (Urecholine®) (VA) Betimol® nicardipine (Cardene®) nifedipine (Adalat®) (VA) nitroglycerin (Nitrobid, Nitrostat®) (VA) nystatin/triamcinolone topical (Mycolog-II®) cefazolin (Kefzol®) cefuroxime (Ceftin®) chloral hydrate (Somnote®, Aquachloral®) chloroquine phosphate (Aralen phosphate®) cimetidine (Tagamet®) (VA) Cipro® citric acid/sodium citrate (Bicitra®) pilocarpine ophthalmic (Isopto Carpine®) polyethylene glycol/electrolytes (Colyte®) Pred Mild® prednisolone (Pediapred®) prednisolone acetate ophthalmic (Pred Forte®) prednisolone sodium phosphate ophthalmic (Inflamase Forte®) prednisone (Deltasone®) promethazine/codeine (Phenergan with Codeine®) digoxin (Lanoxin®) (VA) Dilantin® (VA) diltiazem (Cardizem®) (VA) quinidine sulfate (Quinidex Extentabs®) (VA) Diprolene® dipyridamole (Persantine®) (VA) disopyramide (Norpace®) (VA) doxazosin (Cardura®) doxepin (Sinequan®) Epipen® Epivir® ergoloid mesylates (Ergot®) ergot/caff/bell alk/phenobarb (Cafergot P-B®) erythromycin ethyl succinate (EryPed®, EES®) erythromycin/sulfisoxazole (Pediazole®) silver sulfadiazine topical (Sivadene®) estradiol transdermal (Estraderm®, Alora®, sodium sulfacetamide ophthalmic (Bleph-10®) sulfamethoxazole (Gatanol®) sulfaspirinlazine (Azulfidine®) sulfinpyrazone (Anturane®) (VA) sulfisoxazole (Gantrisin®) sulindac (Clinoril®) fluorometholone ophthalmic (Flarex®, FML timolol ophthalmic (Betimol, Timoptic®) glipizide (Glucotrol, Glucotrol XL®) (VA) guaifenesin/hydrocodone (Vicodin Tuss®) trimethoprim/sulfamethoxazole (Septra®, Bactim®) Hivid® homatropine ophthalmic (Isopto Homatropine®) hydrochlorothiazide (Microzide®) (VA) hydrochlorothiazide/spironolactone (Aldactazide®) (VA) Iletin II insulins® imipramine (Tofranil®) Imitrex® (QL)

Source: http://www.aeholland.com/REGENCEFORMULARY2003.pdf